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EBVB9:BALF1

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Species (Taxon ID) Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4). (10377)
Gene Name(s) No Information Provided.
Protein Name(s) Apoptosis regulator BALF1
External Links
UniProt P0CK58
EMBL V01555
AJ507799
AF401274
AF401276
AF401277
AF401278
PIR C43045
RefSeq YP_401718.2
IntAct P0CK58
GeneID 3783677
Proteomes UP000007640
GO GO:0006915
GO:0043066
InterPro IPR010677
Pfam PF06861

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0043066

negative regulation of apoptotic process

PMID:22230317[1]

ECO:0000314

P

Figure 4 presents the role of BALF1 in regulating apoptosis. After being placed in an environment to cause serum starvation-induced apoptosis, the control pcDNA transfectants showed a statistically significant higher number of apoptotic control cells in comparison to BALF1 transfectants (4A). Part 4B shows 38.9% of apoptotic pcDNA-transfectants, which was about 4-10 fold increase from BALF1-transfectants. Figure 4C represents that the BALF1 expressing cells showed a much higher survival rate in serum starvation conditions which seems to be attributable to suppression of apoptosis.

complete
CACAO 7244

involved_in

GO:0043066

negative regulation of apoptotic process

PMID:22230317[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0016032

viral process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0945

P

Seeded From UniProt

complete

involved_in

GO:0039526

modulation by virus of host apoptotic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1119

P

Seeded From UniProt

complete

part_of

GO:0030430

host cell cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1035
UniProtKB-SubCell:SL-0381

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Hsu, WL et al. (2012) A role for Epstein-Barr viral BALF1 in facilitating tumor formation and metastasis potential. Virus Res. 163 617-27 PubMed GONUTS page