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DANRE:MIB1

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Contents

Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (taxon:7955)
Gene Name(s) mib1 ( synonyms: mib )
Protein Name(s)
  • E3 ubiquitin-protein ligase mib1
  • Protein mind bomb
External Links
UniProt Identifier MIB1_DANRE
UniProt Accessions Q804S5, Q8JHG3,
EMBL AF537301, AF506233,
RefSeq NP_775393.2,
Ensembl ENSDART00000128234,
Pfam PF06701, PF00569,

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

GO:0005886

plasma membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

GO:0005886

plasma membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0039

C

GO:0007275

multicellular organismal development

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0217

P

GO:0008270

zinc ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000433

F

GO:0008270

zinc ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001841

F

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

GO:0016567

protein ubiquitination

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010606

P

GO:0016874

ligase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0436

F

GO:0046872

metal ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010606

F

GO:0046872

metal ion binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0479

F

GO:0007219

Notch signaling pathway

PMID:12530964[1]

IMP: Inferred from Mutant Phenotype

P

Figure 1. ngn1 and deltaA, which are involved in Notch signaling are not as effectively restricted in mind bomb mutant embryos. Additionally, mutant embryonic cells express more huC, which is characteristic of cells that escape lateral inhibition mediated by the Notch pathway.

complete

GO:0004842

ubiquitin-protein ligase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010606

F

GO:0005737

cytoplasm

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

GO:0005886

plasma membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

GO:0005886

plasma membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0039

C

GO:0007219

Notch signaling pathway

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0914

P

GO:0007275

multicellular organismal development

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0217

P

GO:0008270

zinc ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000433

F

GO:0008270

zinc ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001841

F

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

GO:0016567

protein ubiquitination

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010606

P

GO:0016874

ligase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0436

F

GO:0046872

metal ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010606

F

GO:0046872

metal ion binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0479

F


Notes

References

See Help:References for how to manage references in GONUTS.

  1. Itoh M et al. (2003) Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta. Dev Cell 4: 67-82 PubMed GONUTS page
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