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Category:GO:0004152 ! dihydroorotate dehydrogenase activity
name: dihydroorotate dehydrogenase activity
namespace: molecular_function
def: "Catalysis of the reaction: (S)-dihydroorotate + A = AH(2) + orotate." [EC:1.3.5.2, RHEA:18076]
subset: gosubset_prok
synonym: "(DHO) dehydrogenase activity" RELATED [EC:1.3.5.2]
synonym: "(S)-dihydroorotate:quinone oxidoreductase activity" EXACT systematic_synonym [EC:1.3.5.2]
synonym: "DHOdehase activity" EXACT [EC:1.3.5.2]
synonym: "dihydoorotic acid dehydrogenase activity" EXACT [EC:1.3.5.2]
synonym: "dihydroorotate:ubiquinone oxidoreductase activity" NARROW [EC:1.3.5.2]
xref: EC:1.3.5.2
xref: KEGG:R01868
xref: MetaCyc:DIHYDROOROTATE-DEHYDROGENASE-RXN
xref: Reactome:REACT_100074 "(S)-dihydroorotate + ubiquinone => orotate + ubiquinol, Rattus norvegicus"
xref: Reactome:REACT_101561 "(S)-dihydroorotate + ubiquinone => orotate + ubiquinol, Arabidopsis thaliana"
xref: Reactome:REACT_104099 "(S)-dihydroorotate + ubiquinone => orotate + ubiquinol, Caenorhabditis elegans"
xref: Reactome:REACT_105823 "(S)-dihydroorotate + ubiquinone => orotate + ubiquinol, Plasmodium falciparum"
xref: Reactome:REACT_106035 "(S)-dihydroorotate + ubiquinone => orotate + ubiquinol, Danio rerio"
xref: Reactome:REACT_109840 "(S)-dihydroorotate + ubiquinone => orotate + ubiquinol, Sus scrofa"
xref: Reactome:REACT_116075 "(S)-dihydroorotate + ubiquinone => orotate + ubiquinol, Gallus gallus"
xref: Reactome:REACT_32121 "(S)-dihydroorotate + ubiquinone => orotate + ubiquinol, Staphylococcus aureus N315"
xref: Reactome:REACT_32336 "(S)-dihydroorotate + ubiquinone => orotate + ubiquinol, Saccharomyces cerevisiae"
xref: Reactome:REACT_32754 "(S)-dihydroorotate + ubiquinone => orotate + ubiquinol, Xenopus tropicalis"
xref: Reactome:REACT_34767 "(S)-dihydroorotate + ubiquinone => orotate + ubiquinol, Taeniopygia guttata"
xref: Reactome:REACT_669 "(S)-dihydroorotate + ubiquinone => orotate + ubiquinol, Homo sapiens"
xref: Reactome:REACT_77905 "(S)-dihydroorotate + ubiquinone => orotate + ubiquinol, Oryza sativa"
xref: Reactome:REACT_79091 "(S)-dihydroorotate + ubiquinone => orotate + ubiquinol, Gallus gallus"
xref: Reactome:REACT_82404 "(S)-dihydroorotate + ubiquinone => orotate + ubiquinol, Schizosaccharomyces pombe"
xref: Reactome:REACT_87685 "(S)-dihydroorotate + ubiquinone => orotate + ubiquinol, Escherichia coli"
xref: Reactome:REACT_89913 "(S)-dihydroorotate + ubiquinone => orotate + ubiquinol, Drosophila melanogaster"
xref: Reactome:REACT_90116 "(S)-dihydroorotate + ubiquinone => orotate + ubiquinol, Canis familiaris"
xref: Reactome:REACT_96217 "(S)-dihydroorotate + ubiquinone => orotate + ubiquinol, Bos taurus"
xref: Reactome:REACT_98035 "(S)-dihydroorotate + ubiquinone => orotate + ubiquinol, Mus musculus"
xref: Reactome:REACT_99640 "(S)-dihydroorotate + ubiquinone => orotate + ubiquinol, Mycobacterium tuberculosis"
xref: RHEA:18076
is_a: GO:0016635 ! oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor
AmiGO
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