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CONST:CONII

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Species (Taxon ID) Conus striatus (Striated cone). (6493)
Gene Name(s) No Information Provided.
Protein Name(s) Con-ikot-ikot
External Links
UniProt P0CB20
PDB 4U5B
4U5C
4U5D
4U5E
4U5F
4U5G
4U5H
PDBsum 4U5B
4U5C
4U5D
4U5E
4U5F
4U5G
4U5H
ProteinModelPortal P0CB20
ConoServer 3890
GO GO:0035792

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0004970

ionotropic glutamate receptor activity

PMID:19481459[1]

ECO:0000314

F

Fig 4. Con-ikot-ikot specifically targets a subset of iGluRs.

complete

enables

GO:0042802

identical protein binding

PMID:25103405[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P0CB20

F

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0090729

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

part_of

GO:0035792

other organism postsynaptic membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0629

C

Seeded From UniProt

complete

enables

GO:0090729

toxin activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0800

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Walker, CS et al. (2009) A novel Conus snail polypeptide causes excitotoxicity by blocking desensitization of AMPA receptors. Curr. Biol. 19 900-8 PubMed GONUTS page
  2. Chen, L et al. (2014) X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism. Science 345 1021-6 PubMed GONUTS page