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CHICK:O73684

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) cP450cc24 (ECO:0000313 with EMBL:AAC41266.1)
Protein Name(s) 25-hydroxyvitamin D3 24-hydroxylase (ECO:0000313 with EMBL:AAC41266.1)
External Links
UniProt O73684
EMBL AF019142
RefSeq NP_990310.1
UniGene Gga.893
ProteinModelPortal O73684
STRING 9031.ENSGALP00000012629
PaxDb O73684
GeneID 395827
KEGG gga:395827
CTD 1591
eggNOG COG2124
HOGENOM HOG000276540
HOVERGEN HBG099053
KO K07436
PhylomeDB O73684
NextBio 20815895
PRO PR:O73684
GO GO:0020037
GO:0005506
GO:0004497
GO:0016705
Gene3D 1.10.630.10
InterPro IPR001128
IPR017972
IPR002401
Pfam PF00067
PRINTS PR00463
PR00385
SUPFAM SSF48264
PROSITE PS00086

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:1901754

vitamin D3 catabolic process

PMID:9512657[1]

ECO:0000314

direct assay evidence used in manual assertion

P

has_direct_input:(CHEBI:17933)|has_direct_input:(CHEBI:17823)

Seeded From UniProt

complete

involved_in

GO:1990523

bone regeneration

PMID:9101371[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:1901754

vitamin D3 catabolic process

PMID:9101371[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0070576

vitamin D 24-hydroxylase activity

PMID:9101371[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0070576

vitamin D 24-hydroxylase activity

PMID:9512657[1]

ECO:0000314

direct assay evidence used in manual assertion

F

has_direct_input:(CHEBI:17933)|has_direct_input:(CHEBI:17823)

Seeded From UniProt

complete

enables

GO:0005506

iron ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001128
InterPro:IPR002401
InterPro:IPR036396

F

Seeded From UniProt

complete

enables

GO:0016705

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001128
InterPro:IPR002401
InterPro:IPR017972
InterPro:IPR036396

F

Seeded From UniProt

complete

enables

GO:0020037

heme binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001128
InterPro:IPR002401
InterPro:IPR036396

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001128
InterPro:IPR002401
InterPro:IPR017972
InterPro:IPR036396

P

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0004497

monooxygenase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0503

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Jehan, F et al. (1998) Cloning and expression of the chicken 25-hydroxyvitamin D3 24-hydroxylase cDNA. Biochim. Biophys. Acta 1395 259-65 PubMed GONUTS page
  2. 2.0 2.1 2.2 Seo, EG & Norman, AW (1997) Three-fold induction of renal 25-hydroxyvitamin D3-24-hydroxylase activity and increased serum 24,25-dihydroxyvitamin D3 levels are correlated with the healing process after chick tibial fracture. J. Bone Miner. Res. 12 598-606 PubMed GONUTS page