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CANAL:Q5ALT5
Contents
| Species (Taxon ID) | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast). (237561) | |
| Gene Name(s) | MSB2 (ECO:0000313 with CGD:CAL0004775) | |
| Protein Name(s) | Potential cell surface flocculin (ECO:0000313 with EMBL:EAL03648.1) | |
| External Links | ||
| UniProt | Q5ALT5 | |
| EMBL | AACQ01000008 AACQ01000007 | |
| RefSeq | XP_722401.1 XP_722538.1 | |
| STRING | 5476.CAL0004775 | |
| GeneID | 3635830 3635923 | |
| KEGG | cal:CaO19.1490 cal:CaO19.9067 | |
| CGD | CAL0004775 | |
| eggNOG | NOG12793 | |
| OrthoDB | EOG78H456 | |
| Proteomes | UP000000559 | |
| GO | GO:0009986 GO:0005576 GO:0030447 GO:0044182 GO:0031505 GO:1900430 GO:0043410 GO:1900233 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0031505 |
fungal-type cell wall organization |
EXP: Inferred from Experiment |
P |
Congo red (compound that interacts with chitin/interferes with cell wall construction) and caspofungin (inhibitor of the β-(1,3)-glucan synthase) were used on msb2 wildtype and mutant phenotypes to determine sensibility based on msb2 presence. Fig.1A,1A, MSB2 deletion resulted in Congo red sensitivity (250 μg/ml) as opposed to wildtype |
complete | |||
| GO:0005576 |
extracellular region |
IDA: Inferred from Direct Assay |
C |
Seeded From UniProt |
complete | |||
| GO:0005576 |
extracellular region |
IDA: Inferred from Direct Assay |
C |
Seeded From UniProt |
complete | |||
| GO:0009986 |
cell surface |
IDA: Inferred from Direct Assay |
C |
Seeded From UniProt |
complete | |||
| GO:0030447 |
filamentous growth |
IMP: Inferred from Mutant Phenotype |
P |
Seeded From UniProt |
complete | |||
| GO:0031505 |
fungal-type cell wall organization |
IMP: Inferred from Mutant Phenotype |
P |
Seeded From UniProt |
complete | |||
| GO:0043410 |
positive regulation of MAPK cascade |
IMP: Inferred from Mutant Phenotype |
P |
Seeded From UniProt |
complete | |||
| GO:0044182 |
filamentous growth of a population of unicellular organisms |
IMP: Inferred from Mutant Phenotype |
P |
Seeded From UniProt |
complete | |||
| GO:1900233 |
positive regulation of single-species biofilm formation on inanimate substrate |
IMP: Inferred from Mutant Phenotype |
P |
Seeded From UniProt |
complete | |||
| GO:1900430 |
positive regulation of filamentous growth of a population of unicellular organisms |
IMP: Inferred from Mutant Phenotype |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Román, E et al. (2009) Msb2 signaling mucin controls activation of Cek1 mitogen-activated protein kinase in Candida albicans. Eukaryotic Cell 8 1235-49 PubMed GONUTS page
- ↑ Maddi, A et al. (2009) Trifluoromethanesulfonic acid-based proteomic analysis of cell wall and secreted proteins of the ascomycetous fungi Neurospora crassa and Candida albicans. Fungal Genet. Biol. 46 768-81 PubMed GONUTS page
- ↑ Sorgo, AG et al. (2010) Mass spectrometric analysis of the secretome of Candida albicans. Yeast 27 661-72 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Puri, S et al. (2012) Secreted aspartic protease cleavage of Candida albicans Msb2 activates Cek1 MAPK signaling affecting biofilm formation and oropharyngeal candidiasis. PLoS ONE 7 e46020 PubMed GONUTS page
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