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BPMU:TNPA
Contents
| Species (Taxon ID) | Enterobacteria phage Mu (Bacteriophage Mu). (10677) | |
| Gene Name(s) | A | |
| Protein Name(s) | DDE-recombinase A
DDE-transposase A Gene product 03 gp03 Gene product A gpA MuA | |
| External Links | ||
| UniProt | P07636 | |
| EMBL | M11195 M64097 AF083977 V01464 V00868 | |
| PIR | A24746 | |
| RefSeq | NP_050607.1 | |
| PDB | 1BCM 1BCO 1TNS 1TNT 2EZH 2EZI 2EZK 2EZL 4FCY | |
| PDBsum | 1BCM 1BCO 1TNS 1TNT 2EZH 2EZI 2EZK 2EZL 4FCY | |
| ProteinModelPortal | P07636 | |
| SMR | P07636 | |
| DIP | DIP-59984N | |
| GeneID | 2636292 | |
| EvolutionaryTrace | P07636 | |
| Proteomes | UP000002611 | |
| GO | GO:0030430 GO:0003677 GO:0016874 GO:0046872 GO:0004518 GO:0004803 GO:0015074 GO:0006281 GO:0006313 GO:0039693 | |
| Gene3D | 1.10.10.10 1.10.10.60 2.30.30.130 3.30.420.10 | |
| InterPro | IPR009061 IPR009057 IPR015126 IPR003314 IPR004189 IPR012337 IPR015378 IPR009004 IPR011991 | |
| Pfam | PF02914 PF02316 PF09039 PF09299 | |
| SUPFAM | SSF46689 SSF46955 SSF50610 SSF53098 | |
| PROSITE | PS51702 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:1990238 |
double-stranded DNA endodeoxyribonuclease activity |
ECO:0000315 |
F |
WT MuA shows endonuclease activity on pUC19 in OC and SC forms, while domain III defective mutants failed to degrade the plasmid (Figure 2B). |
complete | |||||
|
enables |
GO:1990238 |
double-stranded DNA endodeoxyribonuclease activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0018995 |
host |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004803 |
transposase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004518 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003676 |
nucleic acid binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004803 |
transposase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006313 |
transposition, DNA-mediated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0015074 |
DNA integration |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0015074 |
DNA integration |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0032196 |
transposition |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006260 |
DNA replication |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016874 |
ligase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0039693 |
viral DNA genome replication |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030430 |
host cell cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006310 |
DNA recombination |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0098689 |
latency-replication decision |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004518 |
nuclease activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006281 |
DNA repair |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Choi, W & Harshey, RM (2010) DNA repair by the cryptic endonuclease activity of Mu transposase. Proc. Natl. Acad. Sci. U.S.A. 107 10014-9 PubMed GONUTS page
- ↑ Abdelhakim, AH et al. (2008) Unique contacts direct high-priority recognition of the tetrameric Mu transposase-DNA complex by the AAA+ unfoldase ClpX. Mol. Cell 30 39-50 PubMed GONUTS page
- ↑ Baker, TA & Luo, L (1994) Identification of residues in the Mu transposase essential for catalysis. Proc. Natl. Acad. Sci. U.S.A. 91 6654-8 PubMed GONUTS page
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