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TableEdit
HUMAN:CAMP
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Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status | |
---|---|---|---|---|---|---|---|---|---|---|---|
public |
GO:0001934 |
positive regulation of protein phosphorylation |
PMID:24085296 |
ECO:0000266 |
UniProtKB: |
P |
Figure 1: Fisetin potentiation of HCN2 channels resembled the channel's regulation by cAMP, thereby suggesting that fisetin and cAMP may use similar mechanisms to stabilize the channel's open state |
complete | |||
public |
GO:0042742 |
defense response to bacterium |
PMID:16020269 |
ECO:0000314 |
P |
The human cathelicidin antimicrobial peptide can be cleaved into two peptides, one of which being the antibacterial peptide LL-37. The antibacterial activity of LL-37 against Pseudomonas Aeruginosa, Staphylococcus Aureus, and Staphylococcus Epidermidis was tested using an antibacterial assay. The results showed that at 100 μg/ml, LL-37 was completely bactericidal for all strains of PA, as shown in Figure 2. LL-37 also showed potent bactericidal activity against SA and SE with EC50 values being 1.6 ± 1.5 (n = 3) and 1.31.9 (n 3) μg/ml, respectively. |
complete | ||||
public |
GO:0051873 |
killing by host of symbiont cells |
PMID:16020269 |
ECO:0000314 |
P |
Human cathelicidin antimicrobial peptide has the ability to kill the cells of other organisms. It can be cleaved into two peptides, one of which being the antibacterial peptide LL-37. The antibacterial activity of LL-37 against Pseudomonas aeruginosa, Staphylococcus aureus, and Staphylococcus epidermidis was tested using an antibacterial assay. The results showed that at 100 μg/ml, LL-37 was completely bactericidal for all strains of Pseudomonas aeruginosa (Figure 2). LL-37 also showed potent bactericidal activity against Staphylococcus aureus and Staphylococcus epidermidis with EC50 values being 1.6 ± 1.5 (n = 3) and 1.31.9 (n 3) μg/ml, respectively (Figure 2). |
complete | ||||
public |
GO:0002376 |
immune system process |
PMID:16020269 |
ECO:0000314 |
P |
Human cathelicidin antimicrobial peptide plays a role in immune system processes. It can be cleaved into two peptides, one of which being the antibacterial peptide LL-37. The antibacterial immune activity of LL-37 against Pseudomonas aeruginosa, Staphylococcus aureus, and Staphylococcus epidermidis was tested using an antibacterial assay. The results showed that at 100 μg/ml, LL-37 was completely bactericidal for all strains of Pseudomonas aeruginosa (Figure 2). LL-37 also showed potent bactericidal activity against Staphylococcus aureus and Staphylococcus epidermidis with EC50 values being 1.6 ± 1.5 (n = 3) and 1.31.9 (n 3) μg/ml, respectively (Figure 2). |
complete | ||||
public |
GO:0016045 |
detection of bacterium |
PMID:16020269 |
ECO:0000314 |
P |
Human cathelicidin antimicrobial peptide has the ability to detect bacterial cells and express antibacterial activity against them. It can be cleaved into two peptides, one of which being the antibacterial peptide LL-37. The antibacterial activity of LL-37 against Pseudomonas aeruginosa, Staphylococcus aureus, and Staphylococcus epidermidis was tested using an antibacterial assay. The results showed that at 100 μg/ml, LL-37 was completely bactericidal for all strains of Pseudomonas aeruginosa (Figure 2). LL-37 also showed potent bactericidal activity against Staphylococcus aureus and Staphylococcus epidermidis with EC50 values being 1.6 ± 1.5 (n = 3) and 1.31.9 (n 3) μg/ml, respectively (Figure 2). |
complete | ||||
protected |
involved_in |
GO:0061844 |
antimicrobial humoral immune response mediated by antimicrobial peptide |
PMID:12860195 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:0042581 |
specific granule |
PMID:12759353 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(CL:0000775) |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005615 |
extracellular space |
PMID:12759353 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(UBERON:0006530) |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005615 |
extracellular space |
PMID:18714013 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(UBERON:0006530) |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0070062 |
extracellular exosome |
PMID:23533145 |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:0070062 |
extracellular exosome |
PMID:19056867 |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
part_of:(UBERON:0001088) |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0050830 |
defense response to Gram-positive bacterium |
PMID:12860195 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
occurs_in:(UBERON:0000317) |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0019731 |
antibacterial humoral response |
PMID:12860195 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
occurs_in:(UBERON:0000317) |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005615 |
extracellular space |
PMID:12860195 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(UBERON:0000317) |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0002227 |
innate immune response in mucosa |
PMID:12860195 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
occurs_in:(UBERON:0000317) |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0061844 |
antimicrobial humoral immune response mediated by antimicrobial peptide |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:108443 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0050830 |
defense response to Gram-positive bacterium |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:108443 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0050829 |
defense response to Gram-negative bacterium |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:108443 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0045087 |
innate immune response |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:108443 |
P |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0042581 |
specific granule |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:108443 |
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005615 |
extracellular space |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:105983 |
C |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0001530 |
lipopolysaccharide binding |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000024620 |
F |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0051873 |
killing by host of symbiont cells |
PMID:16177355 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0044140 |
negative regulation of growth of symbiont on or near host surface |
PMID:16177355 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0042742 |
defense response to bacterium |
PMID:21115716 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:0005615 |
extracellular space |
PMID:21115716 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:0005576 |
extracellular region |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001894 |
C |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0006952 |
defense response |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001894 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0042742 |
defense response to bacterium |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR022746 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0061844 |
antimicrobial humoral immune response mediated by antimicrobial peptide |
PMID:7529412 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0045087 |
innate immune response |
PMID:7529412 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0019731 |
antibacterial humoral response |
PMID:7529412 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0050829 |
defense response to Gram-negative bacterium |
PMID:7529412 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0050830 |
defense response to Gram-positive bacterium |
PMID:7529412 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0061844 |
antimicrobial humoral immune response mediated by antimicrobial peptide |
PMID:12759353 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0061844 |
antimicrobial humoral immune response mediated by antimicrobial peptide |
PMID:9182550 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0061844 |
antimicrobial humoral immune response mediated by antimicrobial peptide |
PMID:17012259 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0061844 |
antimicrobial humoral immune response mediated by antimicrobial peptide |
PMID:14978112 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0061844 |
antimicrobial humoral immune response mediated by antimicrobial peptide |
PMID:20209079 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0035821 |
modification of morphology or physiology of other organism |
PMID:23537644 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0061844 |
antimicrobial humoral immune response mediated by antimicrobial peptide |
PMID:23537644 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0050830 |
defense response to Gram-positive bacterium |
PMID:23537644 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0050829 |
defense response to Gram-negative bacterium |
PMID:23537644 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:2000484 |
positive regulation of interleukin-8 secretion |
PMID:14978112 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
occurs_in:(CL:0000312) |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0050829 |
defense response to Gram-negative bacterium |
PMID:14978112 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0001878 |
response to yeast |
PMID:14978112 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0019732 |
antifungal humoral response |
PMID:14978112 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0050830 |
defense response to Gram-positive bacterium |
PMID:14978112 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0019731 |
antibacterial humoral response |
PMID:14978112 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0045087 |
innate immune response |
PMID:14978112 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:0005615 |
extracellular space |
PMID:14978112 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(UBERON:0001089) |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0045087 |
innate immune response |
PMID:12759353 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
occurs_in:(UBERON:0000996) |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0019731 |
antibacterial humoral response |
PMID:12759353 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0050829 |
defense response to Gram-negative bacterium |
PMID:12759353 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0050830 |
defense response to Gram-positive bacterium |
PMID:12759353 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0002544 |
chronic inflammatory response |
PMID:9182550 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
occurs_in:(UBERON:0000014) |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005615 |
extracellular space |
PMID:20421939 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0061844 |
antimicrobial humoral immune response mediated by antimicrobial peptide |
PMID:20421939 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0051838 |
cytolysis by host of symbiont cells |
PMID:20421939 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0045087 |
innate immune response |
PMID:9182550 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
occurs_in:(UBERON:0000014) |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0050830 |
defense response to Gram-positive bacterium |
PMID:9182550 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
occurs_in:(UBERON:0000014) |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0050830 |
defense response to Gram-positive bacterium |
PMID:17012259 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
occurs_in:(UBERON:0000014) |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0045087 |
innate immune response |
PMID:17012259 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
occurs_in:(UBERON:0000014) |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0050829 |
defense response to Gram-negative bacterium |
PMID:20209079 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0019731 |
antibacterial humoral response |
PMID:20209079 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0050830 |
defense response to Gram-positive bacterium |
PMID:20209079 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0045087 |
innate immune response |
PMID:20209079 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0019732 |
antifungal humoral response |
PMID:20209079 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0001878 |
response to yeast |
PMID:20209079 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0042742 |
defense response to bacterium |
PMID:8681941 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:1904724 |
tertiary granule lumen |
Reactome:R-HSA-6798745 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0043312 |
neutrophil degranulation |
Reactome:R-HSA-6798695 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:0035580 |
specific granule lumen |
Reactome:R-HSA-6798749 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0019730 |
antimicrobial humoral response |
Reactome:R-HSA-6803157 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:0005576 |
extracellular region |
Reactome:R-HSA-6801687 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005576 |
extracellular region |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0964 |
C |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0042742 |
defense response to bacterium |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0044 |
P |
Seeded From UniProt |
complete |
Cancel |