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TableEdit
HUMAN:INO80
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| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status | |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
public |
GO:0006302 |
double-strand break repair |
PMID:20687897 |
ECO:0000316 |
UniProtKB:Q9ULG1
|
P |
Figure 1 hINO80 knockdown confers DNA-damage sensitivity and inefficient DSB repair Figure 4 hINO80 binds to the promoters of the Rad54B and XRCC3 genes Figure 5 Re-expression of Rad54B and XRCC3 rescues the DSB repair defect in hINO80-deficient cells |
complete | |||
|
protected |
involved_in |
GO:0006338 |
chromatin remodeling |
GO_REF:0000024 |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
UniProtKB:P53115 |
P |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:2000045 |
regulation of G1/S transition of mitotic cell cycle |
PMID:20237820 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:0071479 |
cellular response to ionizing radiation |
PMID:20687897 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:0070914 |
UV-damage excision repair |
PMID:20855601 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:0051225 |
spindle assembly |
PMID:20237820 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
PMID:20687897 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
enables |
GO:0043014 |
alpha-tubulin binding |
PMID:20237820 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:0034644 |
cellular response to UV |
PMID:18026119 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
part_of |
GO:0031011 |
Ino80 complex |
PMID:21303910 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
protected |
part_of |
GO:0031011 |
Ino80 complex |
PMID:18026119 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:0030307 |
positive regulation of cell growth |
PMID:20237820 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
enables |
GO:0008094 |
DNA-dependent ATPase activity |
PMID:16298340 |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:0010571 |
positive regulation of nuclear cell cycle DNA replication |
PMID:20237820 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:0006302 |
double-strand break repair |
PMID:20687897 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
part_of |
GO:0005634 |
nucleus |
PMID:18026119 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
protected |
part_of |
GO:0005634 |
nucleus |
PMID:16298340 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
protected |
enables |
GO:0003677 |
DNA binding |
PMID:16298340 |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:0000724 |
double-strand break repair via homologous recombination |
PMID:18026119 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:0000070 |
mitotic sister chromatid segregation |
PMID:20237820 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:0043618 |
regulation of transcription from RNA polymerase II promoter in response to stress |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001521025 |
P |
Seeded From UniProt |
complete | |
|
protected |
contributes_to |
GO:0043140 |
ATP-dependent 3'-5' DNA helicase activity |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001521025 |
F |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0043044 |
ATP-dependent chromatin remodeling |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002904112 |
P |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0042766 |
nucleosome mobilization |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001521025 |
P |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0042393 |
histone binding |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002904112 |
F |
Seeded From UniProt |
complete | |
|
protected |
part_of |
GO:0031011 |
Ino80 complex |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0086613 |
C |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0016887 |
ATPase activity |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002904112 |
F |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0006338 |
chromatin remodeling |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002904112 |
P |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0006281 |
DNA repair |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001521025 |
P |
Seeded From UniProt |
complete | |
|
protected |
part_of |
GO:0045111 |
intermediate filament cytoskeleton |
GO_REF:0000052 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
protected |
part_of |
GO:0016604 |
nuclear body |
GO_REF:0000052 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
protected |
part_of |
GO:0005886 |
plasma membrane |
GO_REF:0000052 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
protected |
part_of |
GO:0005654 |
nucleoplasm |
GO_REF:0000052 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:0032508 |
DNA duplex unwinding |
GO_REF:0000108 |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0043140 |
P |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0003677 |
DNA binding |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR020838 |
F |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0005524 |
ATP binding |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000330 |
F |
Seeded From UniProt |
complete | |
|
protected |
part_of |
GO:0005634 |
nucleus |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR031047 |
C |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0006281 |
DNA repair |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR031047 |
P |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0006338 |
chromatin remodeling |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR031047 |
P |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0006351 |
transcription, DNA-templated |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR031047 |
P |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0016887 |
ATPase activity |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR031047 |
F |
Seeded From UniProt |
complete | |
|
protected |
part_of |
GO:0031011 |
Ino80 complex |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR031047 |
C |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0016579 |
protein deubiquitination |
Reactome:R-HSA-5688426 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
part_of |
GO:0005654 |
nucleoplasm |
Reactome:R-HSA-5689544 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
protected |
part_of |
GO:0005874 |
microtubule |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0493 |
C |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0007049 |
cell cycle |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0131 |
P |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0000166 |
nucleotide binding |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0547 |
F |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0016787 |
hydrolase activity |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0378 |
F |
Seeded From UniProt |
complete | |
|
protected |
part_of |
GO:0005694 |
chromosome |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0158 |
C |
Seeded From UniProt |
complete | |
|
protected |
part_of |
GO:0005737 |
cytoplasm |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0963 |
C |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0003779 |
actin binding |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0009 |
F |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0051301 |
cell division |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0132 |
P |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0005524 |
ATP binding |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0067 |
F |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0006310 |
DNA recombination |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0233 |
P |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0006974 |
cellular response to DNA damage stimulus |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0227 |
P |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0006281 |
DNA repair |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0234 |
P |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0003677 |
DNA binding |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0238 |
F |
Seeded From UniProt |
complete | |
|
protected |
part_of |
GO:0005634 |
nucleus |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0539 |
C |
Seeded From UniProt |
complete | |
|
protected |
part_of |
GO:0005856 |
cytoskeleton |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0206 |
C |
Seeded From UniProt |
complete | |
|
protected |
part_of |
GO:0005819 |
spindle |
GO_REF:0000039 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-SubCell:SL-0251 |
C |
Seeded From UniProt |
complete |
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