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MOUSE:GUC2F

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Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

public

GO:0050908

detection of light stimulus involved in visual perception

PMID:17255100

ECO:0000315

P

Figure 2B: At high intensity light stimulus, the a-wave and sensitivity of the scotopic GC2 (GUCY2F) -/- mouse were slightly reduced compared to the WT.

complete
CACAO 4455

protected

involved_in

GO:0050908

detection of light stimulus involved in visual perception

PMID:17255100

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0007168

receptor guanylyl cyclase signaling pathway

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000229249
UniProtKB:P16066
UniProtKB:P20594

P

Seeded From UniProt

complete

protected

involved_in

GO:0007165

signal transduction

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000228924
dictyBase:DDB_G0274569

P

Seeded From UniProt

complete

protected

involved_in

GO:0006182

cGMP biosynthetic process

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000229249
UniProtKB:P16066
UniProtKB:P20594

P

Seeded From UniProt

complete

protected

part_of

GO:0005886

plasma membrane

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000228924
RGD:3195
RGD:620438
RGD:620439
RGD:620851
UniProtKB:P20594
UniProtKB:P9WQ35

C

Seeded From UniProt

complete

protected

enables

GO:0004383

guanylate cyclase activity

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0266136
MGI:MGI:106025
MGI:MGI:106903
MGI:MGI:97371
MGI:MGI:97372
PANTHER:PTN000229249
RGD:2771
RGD:3195
RGD:620438
RGD:620439
UniProtKB:P16066
UniProtKB:P20594
WB:WBGene00001535
WB:WBGene00001538
WB:WBGene00020131
ZFIN:ZDB-GENE-011128-7

F

Seeded From UniProt

complete

protected

enables

GO:0001653

peptide receptor activity

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0266136
PANTHER:PTN000229249

F

Seeded From UniProt

complete

protected

enables

GO:0046982

protein heterodimerization activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:620439

F

Seeded From UniProt

complete

protected

enables

GO:0042803

protein homodimerization activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:620439

F

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0019934

cGMP-mediated signaling

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:620439

P

Seeded From UniProt

complete

protected

part_of

GO:0016020

membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:620439

C

Seeded From UniProt

complete

protected

part_of

GO:0005886

plasma membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:620439

C

Seeded From UniProt

complete

protected

enables

GO:0004383

guanylate cyclase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:620439

F

Seeded From UniProt

complete

protected

enables

GO:0046982

protein heterodimerization activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P51842
ensembl:ENSRNOP00000049500

F

Seeded From UniProt

complete

protected

enables

GO:0042803

protein homodimerization activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P51842
ensembl:ENSRNOP00000049500

F

Seeded From UniProt

complete

protected

involved_in

GO:0019934

cGMP-mediated signaling

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P51842
ensembl:ENSRNOP00000049500

P

Seeded From UniProt

complete

protected

part_of

GO:0016020

membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P51842
ensembl:ENSRNOP00000049500

C

Seeded From UniProt

complete

protected

part_of

GO:0005886

plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P51842
ensembl:ENSRNOP00000049500

C

Seeded From UniProt

complete

protected

enables

GO:0004383

guanylate cyclase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P51842
ensembl:ENSRNOP00000049500

F

Seeded From UniProt

complete

protected

enables

GO:0004672

protein kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR001245

F

Seeded From UniProt

complete

protected

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719

F

Seeded From UniProt

complete

protected

involved_in

GO:0006468

protein phosphorylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR001245

P

Seeded From UniProt

complete

protected

involved_in

GO:0009190

cyclic nucleotide biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001054
InterPro:IPR018297

P

Seeded From UniProt

complete

protected

enables

GO:0016849

phosphorus-oxygen lyase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001054
InterPro:IPR018297

F

Seeded From UniProt

complete

protected

involved_in

GO:0035556

intracellular signal transduction

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001054
InterPro:IPR018297

P

Seeded From UniProt

complete

protected

enables

GO:0004383

guanylate cyclase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:4.6.1.2

F

Seeded From UniProt

complete

protected

enables

GO:0016829

lyase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0456

F

Seeded From UniProt

complete

protected

enables

GO:0005525

GTP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0342

F

Seeded From UniProt

complete

protected

involved_in

GO:0006182

cGMP biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0141

P

Seeded From UniProt

complete

protected

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

protected

involved_in

GO:0050896

response to stimulus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0716

P

Seeded From UniProt

complete

protected

involved_in

GO:0007601

visual perception

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0844

P

Seeded From UniProt

complete

protected

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

protected

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete



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