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TREDE:Q73JV3

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Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

public

GO:1900191

negative regulation of single-species biofilm formation

PMID:24586498

ECO:0000315

P

In Figure 7 the TDE2508-deficient Mutant and the wild type, T. denticola, were both incubated on a polystyrene plate for 2 days. After two days, the amount of biofilm formation and development of bacterial aggregates were measured. The mutant, which was TDE2508-deficient, had a substantial amount of biofilm formation and bacterial aggregates compared to the wild-type. The mutant's ability to produce more biofilm than the wild-type because of the deletion of TDE2508, supports the claim that TDE2508 is involved in the regulation of biofilm formation.

complete
CACAO 10101

public

GO:0030155

regulation of cell adhesion

PMID:24586498

ECO:0000315

P

In Figure 8 the TDE2508-deficient Mutant and the wild type, T. denticola, were both incubated with Ca9-22 epithelial cells for 1 hour. After one hour the Mutant showed significantly more adherence to human gingival epithelial cells at both high and low MOI. Since the figure shows the mutant, which is TDE2508-deficient, as having superior adherence compared to the wild-type, it is clear that the TDE2508 protein plays an important role in regulating cell adhesion.

complete
CACAO 10112

protected

involved_in

GO:0030155

regulation of cell adhesion

PMID:24586498

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:1900191

negative regulation of single-species biofilm formation

PMID:24586498

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete




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