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HUMAN:SMC1A

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Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

protected

part_of

GO:0008278

cohesin complex

PMID:22628566

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:1901673

regulation of mitotic spindle assembly

PMID:11590136

ECO:0000315

mutant phenotype evidence used in manual assertion

P

happens_during:(GO:0033198)

Seeded From UniProt

complete

protected

part_of

GO:0016363

nuclear matrix

PMID:11590136

ECO:0000314

direct assay evidence used in manual assertion

C

exists_during:(GO:0051325)

Seeded From UniProt

complete

protected

part_of

GO:0097431

mitotic spindle pole

PMID:11590136

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0008278

cohesin complex

PMID:11590136

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0032876

negative regulation of DNA endoreduplication

PMID:15917200

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0007062

sister chromatid cohesion

PMID:15917200

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0000776

kinetochore

PMID:11682612

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

enables

GO:0046982

protein heterodimerization activity

PMID:11590136

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q9UQE7

F

Seeded From UniProt

complete

protected

enables

GO:0003723

RNA binding

PMID:22681889

ECO:0007005

high throughput direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

protected

part_of

GO:0030893

meiotic cohesin complex

PMID:21242291

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0009314

response to radiation

PMID:11877377

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0051321

meiotic cell cycle

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z1M9

P

Seeded From UniProt

complete

protected

involved_in

GO:0072423

response to DNA damage checkpoint signaling

PMID:11877377

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

PMID:11076961

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

enables

GO:0003682

chromatin binding

PMID:11076961

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

protected

part_of

GO:0000776

kinetochore

PMID:12199140

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

public

GO:0042127

regulation of cell proliferation

PMID:14608368

ECO:0000314

P

Fig 1 (k) shows that phosphorylation of serine 966 is upregulated in senescent cells compared to proliferating cells.

complete
CACAO 9428

protected

part_of

GO:0005829

cytosol

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005654

nucleoplasm

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0051321

meiotic cell cycle

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9CU62
ensembl:ENSMUSP00000044645

P

Seeded From UniProt

complete

protected

enables

GO:0036033

mediator complex binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9CU62
ensembl:ENSMUSP00000044645

F

Seeded From UniProt

complete

protected

part_of

GO:0030893

meiotic cohesin complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9CU62
ensembl:ENSMUSP00000044645

C

Seeded From UniProt

complete

protected

involved_in

GO:0019827

stem cell population maintenance

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9CU62
ensembl:ENSMUSP00000044645

P

Seeded From UniProt

complete

protected

part_of

GO:0008278

cohesin complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9CU62
ensembl:ENSMUSP00000044645

C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9CU62
ensembl:ENSMUSP00000044645

C

Seeded From UniProt

complete

protected

enables

GO:0003682

chromatin binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9CU62
ensembl:ENSMUSP00000044645

F

Seeded From UniProt

complete

protected

enables

GO:0003682

chromatin binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029683

F

Seeded From UniProt

complete

protected

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010935
InterPro:IPR036277

F

Seeded From UniProt

complete

protected

part_of

GO:0005694

chromosome

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010935
InterPro:IPR036277

C

Seeded From UniProt

complete

protected

involved_in

GO:0006281

DNA repair

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029683

P

Seeded From UniProt

complete

protected

involved_in

GO:0007064

mitotic sister chromatid cohesion

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029683

P

Seeded From UniProt

complete

protected

part_of

GO:0008278

cohesin complex

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029683

C

Seeded From UniProt

complete

protected

involved_in

GO:0051276

chromosome organization

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010935
InterPro:IPR036277

P

Seeded From UniProt

complete

protected

part_of

GO:0000794

condensed nuclear chromosome

PMID:7757074

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0008278

cohesin complex

PMID:11076961

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0007064

mitotic sister chromatid cohesion

PMID:12199140

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0006281

DNA repair

PMID:11877377

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0000070

mitotic sister chromatid segregation

PMID:7757074

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0005654

nucleoplasm

Reactome:R-HSA-3108212
Reactome:R-HSA-2473152
Reactome:R-HSA-2473151
Reactome:R-HSA-2470935
Reactome:R-HSA-2468041
Reactome:R-HSA-2468040
Reactome:R-HSA-2468039
Reactome:R-HSA-9011997

ECO:0000304

author statement supported by traceable reference used in manual assertion








C

Seeded From UniProt

complete

protected

part_of

GO:0000775

chromosome, centromeric region

Reactome:R-HSA-2484822
Reactome:R-HSA-2473151
Reactome:R-HSA-2468287
Reactome:R-HSA-2467811
Reactome:R-HSA-2467809
Reactome:R-HSA-1638821
Reactome:R-HSA-1638803

ECO:0000304

author statement supported by traceable reference used in manual assertion







C

Seeded From UniProt

complete

protected

part_of

GO:0005829

cytosol

Reactome:R-HSA-2545253
Reactome:R-HSA-2545203
Reactome:R-HSA-2467811
Reactome:R-HSA-2467794

ECO:0000304

author statement supported by traceable reference used in manual assertion




C

Seeded From UniProt

complete

protected

part_of

GO:0005694

chromosome

Reactome:R-HSA-2468293
Reactome:R-HSA-2468041
Reactome:R-HSA-2467794
Reactome:R-HSA-2466068

ECO:0000304

author statement supported by traceable reference used in manual assertion




C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

protected

involved_in

GO:0007049

cell cycle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0131

P

Seeded From UniProt

complete

protected

involved_in

GO:0006281

DNA repair

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0234

P

Seeded From UniProt

complete

protected

part_of

GO:0000776

kinetochore

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0995

C

Seeded From UniProt

complete

protected

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

protected

involved_in

GO:0051301

cell division

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0132

P

Seeded From UniProt

complete

protected

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

protected

part_of

GO:0005694

chromosome

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0158
UniProtKB-SubCell:SL-0468

C

Seeded From UniProt

complete

protected

involved_in

GO:0051321

meiotic cell cycle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0469

P

Seeded From UniProt

complete

protected

part_of

GO:0000775

chromosome, centromeric region

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0137

C

Seeded From UniProt

complete

protected

involved_in

GO:0006974

cellular response to DNA damage stimulus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0227

P

Seeded From UniProt

complete

protected

part_of

GO:0000777

condensed chromosome kinetochore

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0149

C

Seeded From UniProt

complete



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