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TableEdit
HUMAN:CDK9
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Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status | |
---|---|---|---|---|---|---|---|---|---|---|---|
public |
GO:0001221 |
transcription cofactor binding |
PMID:9557739 |
ECO:0000314 |
F |
Figure 1b: FLAG tagged PITALRE protein bound to Tat protein complex, discerned with antibody binding |
complete | ||||
protected |
enables |
GO:0008353 |
RNA polymerase II CTD heptapeptide repeat kinase activity |
PMID:9499409 |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | ||
protected |
enables |
GO:0097322 |
7SK snRNA binding |
PMID:11713533 |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | ||
protected |
enables |
GO:0001223 |
transcription coactivator binding |
PMID:12037672 |
ECO:0000353 |
physical interaction evidence used in manual assertion |
UniProtKB:P06400 |
F |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0008024 |
cyclin/CDK positive transcription elongation factor complex |
PMID:9499409 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
protected |
enables |
GO:0003682 |
chromatin binding |
GO_REF:0000024 |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
UniProtKB:Q99J95 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0004693 |
cyclin-dependent protein serine/threonine kinase activity |
PMID:12037670 |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0051147 |
regulation of muscle cell differentiation |
PMID:12037670 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
PMID:19575011 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:1903839 |
positive regulation of mRNA 3'-UTR binding |
PMID:19575011 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
|
Seeded From UniProt |
complete | |
protected |
NOT|involved_in |
GO:0007346 |
regulation of mitotic cell cycle |
PMID:19575011 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:1900364 |
negative regulation of mRNA polyadenylation |
PMID:19575011 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
has_regulation_target:(ENSEMBL:ENSG00000158373) |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:2001168 |
positive regulation of histone H2B ubiquitination |
PMID:19575011 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0033129 |
positive regulation of histone phosphorylation |
PMID:19575011 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:0008023 |
transcription elongation factor complex |
PMID:22195968 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:0016020 |
membrane |
PMID:19946888 |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0071345 |
cellular response to cytokine stimulus |
PMID:17956865 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0071157 |
negative regulation of cell cycle arrest |
PMID:20930849 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0031297 |
replication fork processing |
PMID:20930849 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0031056 |
regulation of histone modification |
PMID:19844166 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:0016605 |
PML body |
PMID:18250157 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
protected |
enables |
GO:0008353 |
RNA polymerase II CTD heptapeptide repeat kinase activity |
PMID:12721286 |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:0008024 |
cyclin/CDK positive transcription elongation factor complex |
PMID:15905409 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0006282 |
regulation of DNA repair |
PMID:20493174 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0070816 |
phosphorylation of RNA polymerase II C-terminal domain |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0037093 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0070816 |
phosphorylation of RNA polymerase II C-terminal domain |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0037093 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0019949 |
P |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0044212 |
transcription regulatory region DNA binding |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1328368 |
F |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0032968 |
positive regulation of transcription elongation from RNA polymerase II promoter |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001936021 |
P |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0030332 |
cyclin binding |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0037093 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0008353 |
RNA polymerase II CTD heptapeptide repeat kinase activity |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0019949 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0008353 |
RNA polymerase II CTD heptapeptide repeat kinase activity |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0019949 |
F |
Seeded From UniProt |
complete | |
public |
GO:0050729 |
positive regulation of inflammatory response |
PMID:26859911 |
ECO:0000314 |
P |
Inhibition of CDK9 lowers uptake of pro-inflammatory cytokines. |
complete | ||||
protected |
enables |
GO:0008134 |
transcription factor binding |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000623455 |
F |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0008024 |
cyclin/CDK positive transcription elongation factor complex |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1328368 |
C |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0006468 |
protein phosphorylation |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0004106 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0006368 |
transcription elongation from RNA polymerase II promoter |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0019949 |
P |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005694 |
chromosome |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000623455 |
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005634 |
nucleus |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0015618 |
C |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0004693 |
cyclin-dependent protein serine/threonine kinase activity |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0004106 |
F |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0000790 |
nuclear chromatin |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001936021 |
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0000307 |
cyclin-dependent protein kinase holoenzyme complex |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001936021 |
C |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0006468 |
protein phosphorylation |
PMID:16109376 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
enables |
GO:0003677 |
DNA binding |
PMID:16109376 |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:0036464 |
cytoplasmic ribonucleoprotein granule |
GO_REF:0000052 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:0005654 |
nucleoplasm |
GO_REF:0000052 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0042493 |
response to drug |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q641Z4 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0010613 |
positive regulation of cardiac muscle hypertrophy |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q641Z4 |
P |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0008134 |
transcription factor binding |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q641Z4 |
F |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005634 |
nucleus |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q641Z4 |
C |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0003682 |
chromatin binding |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q641Z4 |
F |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:2001168 |
positive regulation of histone H2B ubiquitination |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q99J95 |
P |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0044212 |
transcription regulatory region DNA binding |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q99J95 |
F |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0033129 |
positive regulation of histone phosphorylation |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q99J95 |
P |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0019901 |
protein kinase binding |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q99J95 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0017069 |
snRNA binding |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q99J95 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0008353 |
RNA polymerase II CTD heptapeptide repeat kinase activity |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q99J95 |
F |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0008024 |
cyclin/CDK positive transcription elongation factor complex |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q99J95 |
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005634 |
nucleus |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q99J95 |
C |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0003682 |
chromatin binding |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q99J95 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0000978 |
RNA polymerase II proximal promoter sequence-specific DNA binding |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q99J95 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0004672 |
protein kinase activity |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000719 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0005524 |
ATP binding |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000719 |
F |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0006468 |
protein phosphorylation |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000719 |
P |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0008353 |
RNA polymerase II CTD heptapeptide repeat kinase activity |
GO_REF:0000003 |
ECO:0000501 |
evidence used in automatic assertion |
EC:2.7.11.23 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0004693 |
cyclin-dependent protein serine/threonine kinase activity |
GO_REF:0000003 |
ECO:0000501 |
evidence used in automatic assertion |
EC:2.7.11.22 |
F |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0008283 |
cell population proliferation |
PMID:8170997 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:0008023 |
transcription elongation factor complex |
PMID:10866664 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0006368 |
transcription elongation from RNA polymerase II promoter |
PMID:10866664 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0006367 |
transcription initiation from RNA polymerase II promoter |
PMID:10866664 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
enables |
GO:0004693 |
cyclin-dependent protein serine/threonine kinase activity |
PMID:10866664 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | ||
protected |
enables |
GO:0004672 |
protein kinase activity |
PMID:8170997 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0050434 |
positive regulation of viral transcription |
Reactome:R-HSA-167246 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
Reactome:R-HSA-2173796 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0042795 |
snRNA transcription by RNA polymerase II |
Reactome:R-HSA-6807505 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
enables |
GO:0016301 |
kinase activity |
Reactome:R-HSA-112381 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0006366 |
transcription by RNA polymerase II |
Reactome:R-HSA-73857 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:0005654 |
nucleoplasm |
Reactome:R-HSA-9012319 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0004674 |
protein serine/threonine kinase activity |
Reactome:R-HSA-9012319 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | ||
protected |
enables |
GO:0000166 |
nucleotide binding |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0547 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0004674 |
protein serine/threonine kinase activity |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0723 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0016740 |
transferase activity |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0808 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0016301 |
kinase activity |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0418 |
F |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005737 |
cytoplasm |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0963 |
C |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0006281 |
DNA repair |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0234 |
P |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0005524 |
ATP binding |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0067 |
F |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005634 |
nucleus |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0539 |
C |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0006974 |
cellular response to DNA damage stimulus |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0227 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0016310 |
phosphorylation |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0418 |
P |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0016605 |
PML body |
GO_REF:0000039 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-SubCell:SL-0465 |
C |
Seeded From UniProt |
complete |
Cancel |