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PMID:23497616

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Citation

Kuroda, K, Kuang, S, Taketo, MM and Rudnicki, MA (2013) Canonical Wnt signaling induces BMP-4 to specify slow myofibrogenesis of fetal myoblasts. Skelet Muscle 3:5

Abstract

The Wnts are secreted proteins that play important roles in skeletal myogenesis, muscle fiber type diversification, neuromuscular junction formation and muscle stem cell function. How Wnt proteins orchestrate such diverse activities remains poorly understood. Canonical Wnt signaling stabilizes β-catenin, which subsequently translocate to the nucleus to activate the transcription of TCF/LEF family genes.

Links

PubMed PMC3602004 Online version:10.1186/2044-5040-3-5

Keywords

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