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TableEdit
HUMAN:SMUF1
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Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status | |
---|---|---|---|---|---|---|---|---|---|---|---|
public |
GO:2000060 |
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
PMID:21454619 |
ECO:0000315 |
P |
Figure 4 shows how the mutation of this gene affects the regulation of the WFS1 protien |
complete | ||||
protected |
involved_in |
GO:0030514 |
negative regulation of BMP signaling pathway |
PMID:27214554 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
occurs_in:(CL:0002591) |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0061753 |
substrate localization to autophagosome |
PMID:22020285 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
has_target_start_location:(GO:0005739) |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0061736 |
engulfment of target by autophagosome |
PMID:22020285 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
occurs_at:(GO:0005739) |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:1903861 |
positive regulation of dendrite extension |
PMID:23999003 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
occurs_in:(CL:0000148) |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0071211 |
protein targeting to vacuole involved in autophagy |
PMID:22020285 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
has_input:(UniProtKB:P03316) |
Seeded From UniProt |
complete | |
protected |
colocalizes_with |
GO:0005739 |
mitochondrion |
PMID:22020285 |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
UniProtKB:Q9CUN6 |
C |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:2000060 |
positive regulation of ubiquitin-dependent protein catabolic process |
PMID:21454619 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:0070062 |
extracellular exosome |
PMID:19056867 |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
part_of:(UBERON:0001088) |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0070412 |
R-SMAD binding |
PMID:11278251 |
ECO:0000353 |
physical interaction evidence used in manual assertion |
UniProtKB:Q99717 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0070412 |
R-SMAD binding |
PMID:11278251 |
ECO:0000353 |
physical interaction evidence used in manual assertion |
UniProtKB:P84022 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0070412 |
R-SMAD binding |
PMID:11278251 |
ECO:0000353 |
physical interaction evidence used in manual assertion |
UniProtKB:Q15797 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0070411 |
I-SMAD binding |
PMID:12151385 |
ECO:0000353 |
physical interaction evidence used in manual assertion |
UniProtKB:O15105 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0070411 |
I-SMAD binding |
PMID:11278251 |
ECO:0000353 |
physical interaction evidence used in manual assertion |
UniProtKB:O43541 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0048185 |
activin binding |
PMID:16720724 |
ECO:0000303 |
author statement without traceable support used in manual assertion |
F |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0043161 |
proteasome-mediated ubiquitin-dependent protein catabolic process |
PMID:11278251 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0006511 |
ubiquitin-dependent protein catabolic process |
PMID:12151385 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0034394 |
protein localization to cell surface |
PMID:12151385 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0032801 |
receptor catabolic process |
PMID:12151385 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0030579 |
ubiquitin-dependent SMAD protein catabolic process |
PMID:12151385 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0030579 |
ubiquitin-dependent SMAD protein catabolic process |
PMID:11278251 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0030512 |
negative regulation of transforming growth factor beta receptor signaling pathway |
PMID:12151385 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0030512 |
negative regulation of transforming growth factor beta receptor signaling pathway |
PMID:11278251 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0016567 |
protein ubiquitination |
PMID:11278251 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0006611 |
protein export from nucleus |
PMID:11278251 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:0005886 |
plasma membrane |
PMID:12151385 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:0005737 |
cytoplasm |
PMID:12151385 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:0005737 |
cytoplasm |
PMID:11278251 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
protected |
enables |
GO:0061630 |
ubiquitin protein ligase activity |
PMID:12151385 |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
has_direct_input:(UniProtKB:O15105) |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0061630 |
ubiquitin protein ligase activity |
PMID:11278251 |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
has_direct_input:(UniProtKB:O15105) |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0006511 |
ubiquitin-dependent protein catabolic process |
PMID:19937093 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0006511 |
ubiquitin-dependent protein catabolic process |
PMID:10458166 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0030509 |
BMP signaling pathway |
PMID:21572392 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0030154 |
cell differentiation |
PMID:10458166 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:0005737 |
cytoplasm |
PMID:21572392 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
protected |
enables |
GO:0004842 |
ubiquitin-protein transferase activity |
PMID:19937093 |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | ||
protected |
enables |
GO:0004842 |
ubiquitin-protein transferase activity |
PMID:10458166 |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0000209 |
protein polyubiquitination |
PMID:19937093 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
enables |
GO:0061630 |
ubiquitin protein ligase activity |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0259174 |
F |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0045732 |
positive regulation of protein catabolic process |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1202301 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0043161 |
proteasome-mediated ubiquitin-dependent protein catabolic process |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1861728 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0030579 |
ubiquitin-dependent SMAD protein catabolic process |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000135002 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0030514 |
negative regulation of BMP signaling pathway |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0029006 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0016567 |
protein ubiquitination |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0259174 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0006511 |
ubiquitin-dependent protein catabolic process |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0029006 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0006511 |
ubiquitin-dependent protein catabolic process |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0029006 |
P |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005737 |
cytoplasm |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003557 |
C |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0000209 |
protein polyubiquitination |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1202301 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0061734 |
parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9CUN6 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0030279 |
negative regulation of ossification |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9CUN6 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0016567 |
protein ubiquitination |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9CUN6 |
P |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0043025 |
neuronal cell body |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:A0A0G2K612 |
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0030424 |
axon |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:A0A0G2K612 |
C |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0004842 |
ubiquitin-protein transferase activity |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000569 |
F |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0006511 |
ubiquitin-dependent protein catabolic process |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR024928 |
P |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0061630 |
ubiquitin protein ligase activity |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR024928 |
F |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0072659 |
protein localization to plasma membrane |
PMID:22020285 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
enables |
GO:0005543 |
phospholipid binding |
PMID:22020285 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0030514 |
negative regulation of BMP signaling pathway |
PMID:10458166 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0007398 |
ectoderm development |
PMID:10458166 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
enables |
GO:0061630 |
ubiquitin protein ligase activity |
Reactome:R-HSA-4608852 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0060071 |
Wnt signaling pathway, planar cell polarity pathway |
Reactome:R-HSA-4086400 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0030509 |
BMP signaling pathway |
Reactome:R-HSA-201451 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
involved_in |
GO:0007179 |
transforming growth factor beta receptor signaling pathway |
Reactome:R-HSA-2173791 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:0005829 |
cytosol |
Reactome:R-NUL-2176396 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005654 |
nucleoplasm |
Reactome:R-NUL-2169016 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0030154 |
cell differentiation |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0221 |
P |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005737 |
cytoplasm |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0963 |
C |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0016740 |
transferase activity |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0808 |
F |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0016020 |
membrane |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0472 |
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005886 |
plasma membrane |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-1003 |
C |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0016567 |
protein ubiquitination |
GO_REF:0000041 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00143 |
P |
Seeded From UniProt |
complete |
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