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HUMAN:CISD3
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| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status | |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
public |
GO:0005739 |
mitochondrion |
PMID:17376863 |
ECO:0000314 |
C |
mito-NEET is suited to communicate signals between the mitochondria and the rest of the cell as seen in Figure 3. It is characterized by a CDGSH-type zinc finger domain(Figure 1), even though it does not contain any zinc. It is more likely iron containing (Table 1). This protein plays a role in regulating the ETC and oxidative phosphorylation (Figure 5). Yet it's actual role in the etiology of type 2 diabetes and mediating some of the insulin sensitizing thiazolidinediene drugs is yet to be determined. |
complete | ||||
|
protected |
part_of |
GO:0005739 |
mitochondrion |
PMID:17376863 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
protected |
enables |
GO:0046872 |
metal ion binding |
PMID:29259115 |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | ||
|
protected |
enables |
GO:0051537 |
2 iron, 2 sulfur cluster binding |
PMID:29259115 |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:0106034 |
protein maturation by [2Fe-2S] cluster transfer |
PMID:29259115 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
|
Seeded From UniProt |
complete | |
|
protected |
part_of |
GO:0043231 |
intracellular membrane-bounded organelle |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR018967 |
C |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0051537 |
2 iron, 2 sulfur cluster binding |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR018967 |
F |
Seeded From UniProt |
complete | |
|
protected |
part_of |
GO:0005739 |
mitochondrion |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0496 |
C |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0046872 |
metal ion binding |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0479 |
F |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0051537 |
2 iron, 2 sulfur cluster binding |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0001 |
F |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0051536 |
iron-sulfur cluster binding |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0411 |
F |
Seeded From UniProt |
complete |
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