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TableEdit
MOUSE:PTN11
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Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status | |
---|---|---|---|---|---|---|---|---|---|---|---|
protected |
enables |
GO:0019901 |
protein kinase binding |
PMID:17954568 |
ECO:0000353 |
physical interaction evidence used in manual assertion |
UniProtKB:Q9WUN2 |
F |
|
Seeded From UniProt |
complete |
protected |
enables |
GO:0019901 |
protein kinase binding |
PMID:17954568 |
ECO:0000353 |
physical interaction evidence used in manual assertion |
UniProtKB:O88351 |
F |
|
Seeded From UniProt |
complete |
protected |
involved_in |
GO:0032728 |
positive regulation of interferon-beta production |
PMID:17954568 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
|
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0032755 |
positive regulation of interleukin-6 production |
PMID:17954568 |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
UniProtKB:P97797 |
P |
|
Seeded From UniProt |
complete |
protected |
involved_in |
GO:0032760 |
positive regulation of tumor necrosis factor production |
PMID:17954568 |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
UniProtKB:P97797 |
P |
|
Seeded From UniProt |
complete |
protected |
involved_in |
GO:0071364 |
cellular response to epidermal growth factor stimulus |
GO_REF:0000024 |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0070374 |
positive regulation of ERK1 and ERK2 cascade |
GO_REF:0000024 |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005737 |
cytoplasm |
GO_REF:0000024 |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
UniProtKB:Q06124 |
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005634 |
nucleus |
GO_REF:0000024 |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
UniProtKB:Q06124 |
C |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0050839 |
cell adhesion molecule binding |
PMID:19948503 |
ECO:0000353 |
physical interaction evidence used in manual assertion |
UniProtKB:P16573 |
F |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0048013 |
ephrin receptor signaling pathway |
GO_REF:0000024 |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0035335 |
peptidyl-tyrosine dephosphorylation |
GO_REF:0000024 |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0033628 |
regulation of cell adhesion mediated by integrin |
GO_REF:0000024 |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0030971 |
receptor tyrosine kinase binding |
PMID:16885344 |
ECO:0000353 |
physical interaction evidence used in manual assertion |
UniProtKB:P08922 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0004726 |
non-membrane spanning protein tyrosine phosphatase activity |
GO_REF:0000024 |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
UniProtKB:Q06124 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:1990782 |
protein tyrosine kinase binding |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3447 |
F |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0071364 |
cellular response to epidermal growth factor stimulus |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0071260 |
cellular response to mechanical stimulus |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3447 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0070374 |
positive regulation of ERK1 and ERK2 cascade |
PMID:24431450 |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:99604 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0070374 |
positive regulation of ERK1 and ERK2 cascade |
PMID:18827006 |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:87860 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0070374 |
positive regulation of ERK1 and ERK2 cascade |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0061582 |
intestinal epithelial cell migration |
PMID:24675817 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3690333 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0060325 |
face morphogenesis |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0060125 |
negative regulation of growth hormone secretion |
PMID:15520383 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3522021 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0060020 |
Bergmann glial cell differentiation |
PMID:24431450 |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:1346866 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0060020 |
Bergmann glial cell differentiation |
PMID:24431450 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:4868451 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0051463 |
negative regulation of cortisol secretion |
PMID:15520383 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3522021 |
P |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0051428 |
peptide hormone receptor binding |
PMID:15520383 |
ECO:0000353 |
physical interaction evidence used in manual assertion |
UniProtKB:P48356 |
F |
occurs_in:(EMAPA:17536) |
Seeded From UniProt |
complete |
protected |
enables |
GO:0050839 |
cell adhesion molecule binding |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3447 |
F |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0048873 |
homeostasis of number of cells within a tissue |
PMID:24675817 |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:96680 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0048873 |
homeostasis of number of cells within a tissue |
PMID:24675817 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3690333 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0048839 |
inner ear development |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0048806 |
genitalia development |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0048609 |
multicellular organismal reproductive process |
PMID:15520383 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3522021 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0048013 |
ephrin receptor signaling pathway |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0048011 |
neurotrophin TRK receptor signaling pathway |
PMID:12482708 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
acts_upstream_of_or_within |
GO:0048008 |
platelet-derived growth factor receptor signaling pathway |
PMID:18827006 |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:87860 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0046888 |
negative regulation of hormone secretion |
PMID:15520383 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3522021 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0046887 |
positive regulation of hormone secretion |
PMID:15520383 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3522021 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0046825 |
regulation of protein export from nucleus |
PMID:12937170 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2176524 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0046676 |
negative regulation of insulin secretion |
PMID:15520383 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3522021 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0046628 |
positive regulation of insulin receptor signaling pathway |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0046326 |
positive regulation of glucose import |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0045931 |
positive regulation of mitotic cell cycle |
PMID:18827006 |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:87859 |
P |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0043560 |
insulin receptor substrate binding |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3447 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0043274 |
phospholipase binding |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3447 |
F |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0043254 |
regulation of protein complex assembly |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0042593 |
glucose homeostasis |
PMID:15520383 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3522021 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0042445 |
hormone metabolic process |
PMID:15520383 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3522021 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0038127 |
ERBB signaling pathway |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0036302 |
atrioventricular canal development |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0035855 |
megakaryocyte development |
PMID:23509158 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3690333 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0035335 |
peptidyl-tyrosine dephosphorylation |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0035265 |
organ growth |
PMID:15520383 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3522021 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0035264 |
multicellular organism growth |
PMID:24675817 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3690333 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0035264 |
multicellular organism growth |
PMID:15520383 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3522021 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0033629 |
negative regulation of cell adhesion mediated by integrin |
PMID:23509158 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3690333 |
P |
regulates_o_has_participant:(CL:0000233) |
Seeded From UniProt |
complete |
protected |
acts_upstream_of_or_within |
GO:0033628 |
regulation of cell adhesion mediated by integrin |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0033277 |
abortive mitotic cell cycle |
PMID:23509158 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3690333 |
P |
occurs_in:(CL:0000556) |
Seeded From UniProt |
complete |
protected |
part_of |
GO:0032991 |
protein-containing complex |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:Q06124 |
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0032991 |
protein-containing complex |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3447 |
C |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0032528 |
microvillus organization |
PMID:24675817 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3690333 |
P |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0031748 |
D1 dopamine receptor binding |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3447 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0030971 |
receptor tyrosine kinase binding |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3447 |
F |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0030220 |
platelet formation |
PMID:23509158 |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:2146995 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0021697 |
cerebellar cortex formation |
PMID:24431450 |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:1346866 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0021697 |
cerebellar cortex formation |
PMID:24431450 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:4868451 |
P |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0019904 |
protein domain specific binding |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3447 |
F |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0009967 |
positive regulation of signal transduction |
PMID:15520383 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3522021 |
P |
regulates_o_occurs_in:(EMAPA:17536) |
Seeded From UniProt |
complete |
protected |
acts_upstream_of_or_within |
GO:0009755 |
hormone-mediated signaling pathway |
PMID:15520383 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
occurs_in:(EMAPA:17536) |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0007507 |
heart development |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0007420 |
brain development |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0007409 |
axonogenesis |
PMID:12482708 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
protected |
acts_upstream_of_or_within |
GO:0007229 |
integrin-mediated signaling pathway |
PMID:23509158 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3690333 |
P |
occurs_in:(CL:0000556) |
Seeded From UniProt |
complete |
protected |
acts_upstream_of_or_within |
GO:0007173 |
epidermal growth factor receptor signaling pathway |
PMID:18827006 |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:87859 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0006641 |
triglyceride metabolic process |
PMID:15520383 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3522021 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0006629 |
lipid metabolic process |
PMID:15520383 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3522021 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0006470 |
protein dephosphorylation |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3447 |
P |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005829 |
cytosol |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3447 |
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005739 |
mitochondrion |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3447 |
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005737 |
cytoplasm |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:Q06124 |
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005634 |
nucleus |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:Q06124 |
C |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0005158 |
insulin receptor binding |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:Q06124 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0005158 |
insulin receptor binding |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3447 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0005070 |
SH3/SH2 adaptor activity |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:Q06124 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0004726 |
non-membrane spanning protein tyrosine phosphatase activity |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:Q06124 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0004725 |
protein tyrosine phosphatase activity |
PMID:18827006 |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | ||
protected |
enables |
GO:0004725 |
protein tyrosine phosphatase activity |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:Q06124 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0004725 |
protein tyrosine phosphatase activity |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3447 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0004721 |
phosphoprotein phosphatase activity |
PMID:15273746 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3050284 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0004721 |
phosphoprotein phosphatase activity |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:Q06124 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0001784 |
phosphotyrosine residue binding |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:Q06124 |
F |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0000187 |
activation of MAPK activity |
PMID:15273746 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3050284 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0000187 |
activation of MAPK activity |
PMID:12937170 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2176524 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0000077 |
DNA damage checkpoint |
PMID:12937170 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2176524 |
P |
Seeded From UniProt |
complete | |
protected |
enables |
GO:1990782 |
protein tyrosine kinase binding |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P41499 |
F |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0071260 |
cellular response to mechanical stimulus |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P41499 |
P |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0050839 |
cell adhesion molecule binding |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P41499 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0043560 |
insulin receptor substrate binding |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P41499 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0043274 |
phospholipase binding |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P41499 |
F |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0032991 |
protein-containing complex |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P41499 |
C |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0031748 |
D1 dopamine receptor binding |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P41499 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0030971 |
receptor tyrosine kinase binding |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P41499 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0019904 |
protein domain specific binding |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P41499 |
F |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0006470 |
protein dephosphorylation |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P41499 |
P |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005829 |
cytosol |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P41499 |
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005739 |
mitochondrion |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P41499 |
C |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0005158 |
insulin receptor binding |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P41499 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0004725 |
protein tyrosine phosphatase activity |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P41499 |
F |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0071364 |
cellular response to epidermal growth factor stimulus |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0070374 |
positive regulation of ERK1 and ERK2 cascade |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0060325 |
face morphogenesis |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0048839 |
inner ear development |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0048806 |
genitalia development |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0048013 |
ephrin receptor signaling pathway |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0046628 |
positive regulation of insulin receptor signaling pathway |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0046326 |
positive regulation of glucose import |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0043254 |
regulation of protein complex assembly |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0038127 |
ERBB signaling pathway |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0036302 |
atrioventricular canal development |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0035335 |
peptidyl-tyrosine dephosphorylation |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0033628 |
regulation of cell adhesion mediated by integrin |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0032991 |
protein-containing complex |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06124 |
C |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0007507 |
heart development |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0007420 |
brain development |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06124 |
P |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005737 |
cytoplasm |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06124 |
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005634 |
nucleus |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06124 |
C |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0005158 |
insulin receptor binding |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06124 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0005070 |
SH3/SH2 adaptor activity |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06124 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0004726 |
non-membrane spanning protein tyrosine phosphatase activity |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06124 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0004725 |
protein tyrosine phosphatase activity |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06124 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0004721 |
phosphoprotein phosphatase activity |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06124 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0001784 |
phosphotyrosine residue binding |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06124 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0004725 |
protein tyrosine phosphatase activity |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000242 |
F |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0006470 |
protein dephosphorylation |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000242 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0016311 |
dephosphorylation |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000387 |
P |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0016791 |
phosphatase activity |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000387 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0004725 |
protein tyrosine phosphatase activity |
GO_REF:0000003 |
ECO:0000501 |
evidence used in automatic assertion |
EC:3.1.3.48 |
F |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005829 |
cytosol |
Reactome:R-MMU-914067 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0016787 |
hydrolase activity |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0378 |
F |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005737 |
cytoplasm |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0963 |
C |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0004721 |
phosphoprotein phosphatase activity |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0904 |
F |
Seeded From UniProt |
complete |
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