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MOUSE:RO52
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Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status | |
---|---|---|---|---|---|---|---|---|---|---|---|
public |
GO:0032088 |
negative regulation of NF-kappaB transcription factor activity |
PMID:19494276 |
ECO:0000269 |
P |
Fig 8A: Analyses using a NF-κB-driven luciferase reporter for cells stimulated with LPS or poly(I:C). LPS- and poly(I:C)-induced luciferase activity was significantly higher in Trim21−/− cells than in Trim21+/+ cells |
complete | ||||
public |
GO:0032088 |
negative regulation of NF-kappaB transcription factor activity |
PMID:19494276 |
ECO:0000269 |
P |
Anaylses using a NF-kB driven luciferase reporter for cells stimulated with LPS or Poly (I:C) . As shown in Fig 8A, the LPS and Poly (I:C) - induced luciferase activity was significantly higher in Trim -/- than in Trim +/- |
complete | ||||
protected |
involved_in |
GO:0034341 |
response to interferon-gamma |
GO_REF:0000024 |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
UniProtKB:P19474 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0010508 |
positive regulation of autophagy |
GO_REF:0000024 |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
UniProtKB:P19474 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0090086 |
negative regulation of protein deubiquitination |
GO_REF:0000024 |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
UniProtKB:P19474 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0051865 |
protein autoubiquitination |
GO_REF:0000024 |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
UniProtKB:P19474 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0045787 |
positive regulation of cell cycle |
GO_REF:0000024 |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
UniProtKB:P19474 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0032088 |
negative regulation of NF-kappaB transcription factor activity |
GO_REF:0000024 |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
UniProtKB:P19474 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0031648 |
protein destabilization |
GO_REF:0000024 |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
UniProtKB:P19474 |
P |
Seeded From UniProt |
complete | |
protected |
colocalizes_with |
GO:0019005 |
SCF ubiquitin ligase complex |
GO_REF:0000024 |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
UniProtKB:P19474 |
C |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0016567 |
protein ubiquitination |
GO_REF:0000024 |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
UniProtKB:P19474 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0006513 |
protein monoubiquitination |
GO_REF:0000024 |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
UniProtKB:P19474 |
P |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005737 |
cytoplasm |
GO_REF:0000024 |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
UniProtKB:P19474 |
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005634 |
nucleus |
GO_REF:0000024 |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
UniProtKB:P51965 |
C |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0004842 |
ubiquitin-protein transferase activity |
GO_REF:0000024 |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
UniProtKB:P19474 |
F |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0000209 |
protein polyubiquitination |
GO_REF:0000024 |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
UniProtKB:P19474 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:1902187 |
negative regulation of viral release from host cell |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:P19474 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0090086 |
negative regulation of protein deubiquitination |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:P19474 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0070206 |
protein trimerization |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:P19474 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0051865 |
protein autoubiquitination |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:P19474 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0051091 |
positive regulation of DNA-binding transcription factor activity |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:P19474 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0045787 |
positive regulation of cell cycle |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:P19474 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0045087 |
innate immune response |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:P19474 |
P |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0042802 |
identical protein binding |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:P19474 |
F |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0034341 |
response to interferon-gamma |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:P19474 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0032897 |
negative regulation of viral transcription |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:P19474 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0032088 |
negative regulation of NF-kappaB transcription factor activity |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:P19474 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0031648 |
protein destabilization |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:P19474 |
P |
Seeded From UniProt |
complete | |
protected |
colocalizes_with |
GO:0019005 |
SCF ubiquitin ligase complex |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:P19474 |
C |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0016567 |
protein ubiquitination |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:P19474 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0010508 |
positive regulation of autophagy |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:P19474 |
P |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0006513 |
protein monoubiquitination |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:P19474 |
P |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005737 |
cytoplasm |
PMID:11331580 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
protected |
part_of |
GO:0005737 |
cytoplasm |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:P19474 |
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005654 |
nucleoplasm |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:P19474 |
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005634 |
nucleus |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:P19474 |
C |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0004842 |
ubiquitin-protein transferase activity |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:P19474 |
F |
Seeded From UniProt |
complete | |
protected |
acts_upstream_of_or_within |
GO:0000209 |
protein polyubiquitination |
GO_REF:0000096 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
UniProtKB:P19474 |
P |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0008270 |
zinc ion binding |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000315 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0046872 |
metal ion binding |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR018957 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0046872 |
metal ion binding |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0479 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0016740 |
transferase activity |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0808 |
F |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0007049 |
cell cycle |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0131 |
P |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0003723 |
RNA binding |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0694 |
F |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0003677 |
DNA binding |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0238 |
F |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005634 |
nucleus |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0539 |
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0031410 |
cytoplasmic vesicle |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0968 |
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005737 |
cytoplasm |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0963 |
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0000932 |
P-body |
GO_REF:0000039 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-SubCell:SL-0230 |
C |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005776 |
autophagosome |
GO_REF:0000039 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-SubCell:SL-0023 |
C |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0016567 |
protein ubiquitination |
GO_REF:0000041 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00143 |
P |
Seeded From UniProt |
complete |
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