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TableEdit
STRPY:HASA
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| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status | |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
public |
GO:0050501 |
hyaluronan synthase activity |
PMID:8366070 |
ECO:0000315 |
F |
Based on fig. 1, hyaluronan(HA) synthase gene was identified based on the fact that Tn insertional mutagenesis caused the band on the gel. Fig. 4 shows the presence of HasA in E. coli with pPD41-delta5 (lane C) and pPD41-deltaPstI(lane D) while table 1 shows positive HA production for strains that contain the plasmid. Strains with pPD41-deltaPstI show little activity for HA synthesis because no HasB present which is required for the reaction. |
complete | ||||
|
public |
GO:0090609 |
single-species submerged biofilm formation |
PMID:16135223 |
ECO:0000315 |
P |
Figure 5. shows that HasA mutants were unable to form biofilm. |
complete | ||||
|
public |
Contributes to |
GO:0009405 |
pathogenesis |
PMID:21921933 |
ECO:0000315 |
P |
Table 2. HasA is involved in the production of the hyaluronic acid capsule. Hyaluronic acid mimics host connective tissue. |
complete | |||
|
public |
Contributes to |
GO:0009405 |
pathogenesis |
PMID:23131832 |
ECO:0000314 |
P |
Figure 2 Strep A species lack hasABC genes needed for hyaluronic acid capsule formation, which contributes to Strep species pathogenesis. |
complete | |||
|
protected |
involved_in |
GO:0090609 |
single-species submerged biofilm formation |
PMID:16135223 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
enables |
GO:0050501 |
hyaluronan synthase activity |
GO_REF:0000003 |
ECO:0000501 |
evidence used in automatic assertion |
EC:2.4.1.212 |
F |
Seeded From UniProt |
complete | |
|
protected |
part_of |
GO:0005886 |
plasma membrane |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-1003 |
C |
Seeded From UniProt |
complete | |
|
protected |
part_of |
GO:0016020 |
membrane |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0472 |
C |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0016740 |
transferase activity |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0808 |
F |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0016757 |
transferase activity, transferring glycosyl groups |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0328 |
F |
Seeded From UniProt |
complete | |
|
protected |
part_of |
GO:0016021 |
integral component of membrane |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0812 |
C |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0009405 |
pathogenesis |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0843 |
P |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0030213 |
hyaluronan biosynthetic process |
GO_REF:0000041 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00341 |
P |
Seeded From UniProt |
complete |
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