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STRTR:E7AXS8

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Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

public

GO:0004398

histidine decarboxylase activity

PMID:22429258

ECO:0000270

F

Figure 2A shows that at the pH values 7.0, 6.2, and 5.5 the OD600 rapidly increased between 8 and 24 h of incubation reaching at 48 h the maximum values, corresponding to cell concentrations between 9.2 and 8.8 log CFU/mL. Also, in Figure in 3A, histamine rapidly accumulated at pH 7.0, 6.2, and 5.5 and a maximum concentration of about 350 mg/L was reached after 24 h. In both cases the production of histamine increased concomitantly with the cell number with a relatively small further rise during the stationary phase. In all cultures the maximum histamine levels were reached at the end of active growth. Histamine was detectable (10 to 55 mg/L) even when growth was strongly inhibited.The HdcA decarboxylase of this strain is very active since the exponential phase under different conditions characterizing the 1st step of the cheesemaking process. In addition, the enzyme is even more active outside the cells and its action is not significantly limited by the conditions found during the cheese ripening process. In this framework, the death and lysis of the starter cultures can be a factor which strengthens the risk of histamine accumulation during cheese ripening when temperature, pH, and NaCl concentration allow an intense activity of this HdcA enzyme.

complete
CACAO 4004

protected

enables

GO:0004398

histidine decarboxylase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003427
InterPro:IPR016106

F

Seeded From UniProt

complete

protected

involved_in

GO:0006520

cellular amino acid metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016104
InterPro:IPR016105

P

Seeded From UniProt

complete

protected

involved_in

GO:0006547

histidine metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003427

P

Seeded From UniProt

complete

protected

enables

GO:0016831

carboxy-lyase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016104
InterPro:IPR016105

F

Seeded From UniProt

complete

protected

enables

GO:0016829

lyase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0456

F

Seeded From UniProt

complete

protected

enables

GO:0016831

carboxy-lyase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0210

F

Seeded From UniProt

complete

protected

involved_in

GO:0006547

histidine metabolic process

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000397758

P

Seeded From UniProt

complete

protected

enables

GO:0004398

histidine decarboxylase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000397758

F

Seeded From UniProt

complete




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