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PMID:22024547
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| Citation |
Zhang, D, Gu, T, Forsberg, E, Efendic, S, Brismar, K and Gu, HF (2011) Genetic and functional effects of membrane metalloendopeptidase on diabetic nephropathy development. Am. J. Nephrol. 34:483-90 |
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| Abstract |
Vasopeptidase as an agent inhibits membrane metalloendopeptidase (MME, also known as neutral endopeptidase). MME is widely distributed in the body and particularly abundant in the kidney. The MME gene is located on chromosome 3q25.1 within a linkage region for diabetic nephropathy (DN). The present study aims to evaluate the genetic and functional effects of MME in the development of DN. |
| Links |
PubMed Online version:10.1159/000333006 |
| Keywords |
Adult; Case-Control Studies; Diabetic Nephropathies/enzymology; Diabetic Nephropathies/genetics; Female; Genetic Association Studies; Humans; Male; Metalloendopeptidases/physiology; Middle Aged |
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