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PMID:20071673
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Citation |
Craig, SE, Thummel, R, Ahmed, H, Vasta, GR, Hyde, DR and Hitchcock, PF (2010) The zebrafish galectin Drgal1-l2 is expressed by proliferating Müller glia and photoreceptor progenitors and regulates the regeneration of rod photoreceptors. Invest. Ophthalmol. Vis. Sci. 51:3244-52 |
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Abstract |
The purpose of this study was to identify secreted proteins in the retina of the adult zebrafish that are induced by the selective death of photoreceptors and to test experimentally the function of these proteins during the regeneration of photoreceptors. |
Links |
PubMed PMC2891476 Online version:10.1167/iovs.09-4879 |
Keywords |
Animals; Cell Count; Cell Death; Cell Proliferation; Electroporation; Galectins/genetics; Galectins/metabolism; Immunoblotting; In Situ Hybridization; Light; Microglia/metabolism; Microglia/pathology; Morpholines/pharmacology; Photoreceptor Cells, Vertebrate/pathology; Photoreceptor Cells, Vertebrate/radiation effects; RNA, Messenger/metabolism; Radiation Injuries, Experimental/metabolism; Radiation Injuries, Experimental/pathology; Regeneration/physiology; Retinal Rod Photoreceptor Cells/physiology; Reverse Transcriptase Polymerase Chain Reaction; Stem Cells/metabolism; Zebrafish; Zebrafish Proteins/genetics; Zebrafish Proteins/metabolism |
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