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Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

public

GO:0014069

postsynaptic density

PMID:21664258

ECO:0000315

C

Figure 2A- from Synaptosomal fraction found in postsynaptic density fraction of wild type and adult heterozygous reeler mice

complete
CACAO 2357

public

GO:0043005

neuron projection

PMID:21664258

ECO:0000315

C

Figure 2A- from Synaptosomal fraction found in postsynaptic density fraction of wild type and adult heterozygous reeler mice.

complete
CACAO 2358

public

GO:0014069

postsynaptic density

PMID:21558424

ECO:0000315

C

Figure 6A and C, A decrease of PSD proteins in postsynaptic density fraction. There was a decrease in homer 1 protein in mutant Shank3 mice. Similar results was seen in figure 6E, confirmed by quantitative analyses.

complete
CACAO 3129

protected

part_of

GO:0044309

neuron spine

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z214-2

C

Seeded From UniProt

complete

protected

involved_in

GO:1902950

regulation of dendritic spine maintenance

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z214-2

P

Seeded From UniProt

complete

protected

involved_in

GO:0051966

regulation of synaptic transmission, glutamatergic

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z214-2

P

Seeded From UniProt

complete

protected

part_of

GO:0014069

postsynaptic density

PMID:21144999

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(UBERON:0005377)|part_of:(UBERON:0004167)|part_of:(UBERON:0007631)

Seeded From UniProt

complete

protected

part_of

GO:0043005

neuron projection

PMID:21664258

ECO:0000315

mutant phenotype evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0014069

postsynaptic density

PMID:21558424

ECO:0000315

mutant phenotype evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0014069

postsynaptic density

PMID:21664258

ECO:0000315

mutant phenotype evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0051262

protein tetramerization

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z214-2

P

Seeded From UniProt

complete

protected

involved_in

GO:2001257

regulation of cation channel activity

PMID:14505576

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:2001256

regulation of store-operated calcium entry

PMID:14505576

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0014069

postsynaptic density

PMID:21558424

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0014069

postsynaptic density

PMID:21664258

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0090279

regulation of calcium ion import

PMID:14505576

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0043005

neuron projection

PMID:21795692

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0002608)

Seeded From UniProt

complete

protected

part_of

GO:0099524

postsynaptic cytosol

PMID:24530450

ECO:0006042

cell fractionation evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0099524

postsynaptic cytosol

PMID:24530450

ECO:0006003

electron microscopy evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0098978

glutamatergic synapse

PMID:11418862

ECO:0006063

over expression analysis evidence used in manual assertion

C

part_of:(UBERON:0002037)

Seeded From UniProt

complete

protected

part_of

GO:0098978

glutamatergic synapse

PMID:11418862

ECO:0006013

patch-clamp recording evidence used in manual assertion

C

part_of:(UBERON:0002037)

Seeded From UniProt

complete

protected

involved_in

GO:0098962

regulation of postsynaptic neurotransmitter receptor activity

PMID:11418862

ECO:0006063

over expression analysis evidence used in manual assertion

P

  • occurs_in:(GO:0098978)
  • occurs_in:(UBERON:0000061)
  • occurs_in:(UBERON:0002037)

Seeded From UniProt

complete

protected

involved_in

GO:0098962

regulation of postsynaptic neurotransmitter receptor activity

PMID:11418862

ECO:0006013

patch-clamp recording evidence used in manual assertion

P

  • occurs_in:(GO:0098978)
  • occurs_in:(UBERON:0000061)
  • occurs_in:(UBERON:0002037)

Seeded From UniProt

complete

protected

involved_in

GO:2001256

regulation of store-operated calcium entry

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1347345
PANTHER:PTN000857479

P

Seeded From UniProt

complete

protected

part_of

GO:0043005

neuron projection

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1347345
PANTHER:PTN000099620
RGD:628725

C

Seeded From UniProt

complete

protected

enables

GO:0035256

G protein-coupled glutamate receptor binding

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000857479
RGD:620705
RGD:628725

F

Seeded From UniProt

complete

protected

part_of

GO:0030425

dendrite

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000099620
RGD:620705
RGD:628725

C

Seeded From UniProt

complete

protected

part_of

GO:0014069

postsynaptic density

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1347345
MGI:MGI:1347359
PANTHER:PTN000099620
RGD:628725

C

Seeded From UniProt

complete

protected

involved_in

GO:0007216

G protein-coupled glutamate receptor signaling pathway

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000857479
RGD:628725

P

Seeded From UniProt

complete

protected

part_of

GO:0005886

plasma membrane

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1347345
PANTHER:PTN000857479

C

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1347345
MGI:MGI:1347354
PANTHER:PTN000857479
UniProtKB:Q9NSB8

C

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:1902950

regulation of dendritic spine maintenance

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:628725

P

Seeded From UniProt

complete

protected

enables

GO:0099186

structural constituent of postsynapse

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:628725

F

Seeded From UniProt

complete

protected

part_of

GO:0098978

glutamatergic synapse

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:628725

C

Seeded From UniProt

complete

protected

part_of

GO:0098794

postsynapse

PMID:24554721

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

enables

GO:0097110

scaffold protein binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:628725

F

Seeded From UniProt

complete

protected

enables

GO:0060090

molecular adaptor activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:628725

F

Seeded From UniProt

complete

protected

colocalizes_with

GO:0060076

excitatory synapse

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:628725

C

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0051966

regulation of synaptic transmission, glutamatergic

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:628725

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0051928

positive regulation of calcium ion transport

PMID:18268005

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3526529

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0051592

response to calcium ion

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q86YM7

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0051262

protein tetramerization

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:628725

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0048875

chemical homeostasis within a tissue

PMID:15294147

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3526529

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0048741

skeletal muscle fiber development

PMID:18268005

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3526529

P

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0048148

behavioral response to cocaine

PMID:15294147

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3526529

P

Seeded From UniProt

complete

protected

enables

GO:0046982

protein heterodimerization activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:628725

F

Seeded From UniProt

complete

protected

part_of

GO:0045202

synapse

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:628725

C

Seeded From UniProt

complete

protected

part_of

GO:0045177

apical part of cell

PMID:12860966

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(EMAPA:35651)
  • part_of:(CL:0002064)

Seeded From UniProt

complete

protected

enables

GO:0044325

ion channel binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q86YM7

F

Seeded From UniProt

complete

protected

part_of

GO:0044309

neuron spine

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:628725

C

Seeded From UniProt

complete

protected

part_of

GO:0043198

dendritic shaft

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:628725

C

Seeded From UniProt

complete

protected

part_of

GO:0043034

costamere

PMID:18268005

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0043025

neuronal cell body

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:628725

C

Seeded From UniProt

complete

protected

part_of

GO:0043005

neuron projection

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:628725

C

Seeded From UniProt

complete

protected

enables

GO:0042802

identical protein binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:628725

F

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0035418

protein localization to synapse

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:628725

P

Seeded From UniProt

complete

protected

enables

GO:0035256

G protein-coupled glutamate receptor binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:628725

F

Seeded From UniProt

complete

protected

enables

GO:0031802

type 5 metabotropic glutamate receptor binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:628725

F

Seeded From UniProt

complete

protected

part_of

GO:0030425

dendrite

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:628725

C

Seeded From UniProt

complete

protected

part_of

GO:0030424

axon

PMID:23791195

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0030018

Z disc

PMID:18268005

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(EMAPA:35578)

Seeded From UniProt

complete

protected

part_of

GO:0016020

membrane

PMID:15579147

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0014069

postsynaptic density

PMID:24613359

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0014069

postsynaptic density

PMID:23791195

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0014069

postsynaptic density

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:628725

C

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0007216

G protein-coupled glutamate receptor signaling pathway

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:628725

P

Seeded From UniProt

complete

protected

part_of

GO:0005886

plasma membrane

PMID:12176012

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

PMID:12176012

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

enables

GO:0005102

signaling receptor binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:628725

F

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0003009

skeletal muscle contraction

PMID:18268005

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3526529

P

Seeded From UniProt

complete

protected

involved_in

GO:0099173

postsynapse organization

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0099186

P

Seeded From UniProt

complete

protected

involved_in

GO:0051592

response to calcium ion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q86YM7
ensembl:ENSP00000334382

P

Seeded From UniProt

complete

protected

enables

GO:0044325

ion channel binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q86YM7
ensembl:ENSP00000334382

F

Seeded From UniProt

complete

protected

acts_upstream_of_or_within

GO:0007216

G protein-coupled glutamate receptor signaling pathway

PMID:9808458

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0030054

cell junction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0965

C

Seeded From UniProt

complete

protected

part_of

GO:0042995

cell projection

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0966

C

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

protected

part_of

GO:0045211

postsynaptic membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0628

C

Seeded From UniProt

complete

protected

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

protected

part_of

GO:0045202

synapse

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0770
UniProtKB-SubCell:SL-0258

C

Seeded From UniProt

complete

protected

part_of

GO:0005886

plasma membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003

C

Seeded From UniProt

complete

protected

part_of

GO:0043197

dendritic spine

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0284

C

Seeded From UniProt

complete

protected

part_of

GO:0014069

postsynaptic density

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0297

C

Seeded From UniProt

complete



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