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HUMAN:MDR1

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Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

protected

enables

GO:0090554

phosphatidylcholine-translocating ATPase activity

PMID:8898203

ECO:0000314

direct assay evidence used in manual assertion

F

part_of:(GO:0045332)

Seeded From UniProt

complete

protected

part_of

GO:0016324

apical plasma membrane

PMID:8898203

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0099040

ceramide translocation

PMID:8898203

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

enables

GO:0099038

ceramide-translocating ATPase activity

PMID:8898203

ECO:0000314

direct assay evidence used in manual assertion

F

part_of:(GO:0099040)

Seeded From UniProt

complete

protected

involved_in

GO:0045332

phospholipid translocation

PMID:8898203

ECO:0000314

direct assay evidence used in manual assertion

P

transports_or_maintains_localization_of:(CHEBI:64482)|transports_or_maintains_localization_of:(CHEBI:16038)

Seeded From UniProt

complete

protected

enables

GO:0090555

phosphatidylethanolamine-translocating ATPase activity

PMID:8898203

ECO:0000314

direct assay evidence used in manual assertion

F

part_of:(GO:0045332)

Seeded From UniProt

complete

protected

involved_in

GO:2001225

regulation of chloride transport

PMID:7828597

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0047484

regulation of response to osmotic stress

PMID:7828597

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:1901529

positive regulation of anion channel activity

PMID:7828597

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0070062

extracellular exosome

PMID:23533145

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0070062

extracellular exosome

PMID:19056867

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(UBERON:0001088)

Seeded From UniProt

complete

protected

involved_in

GO:0072089

stem cell proliferation

PMID:19384922

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0009986

cell surface

PMID:19384922

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0000086

G2/M transition of mitotic cell cycle

PMID:19384922

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

enables

GO:0099038

ceramide-translocating ATPase activity

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97570
PANTHER:PTN002516971
UniProtKB:P08183

F

Seeded From UniProt

complete

protected

enables

GO:0090555

phosphatidylethanolamine-translocating ATPase activity

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97570
PANTHER:PTN002516971
UniProtKB:P08183

F

Seeded From UniProt

complete

protected

enables

GO:0090554

phosphatidylcholine-translocating ATPase activity

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97570
PANTHER:PTN002516971
UniProtKB:P08183

F

Seeded From UniProt

complete

protected

enables

GO:0042626

ATPase activity, coupled to transmembrane movement of substances

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10613
EcoGene:EG11405
FB:FBgn0004513
MGI:MGI:97570
MGI:MGI:98483
PANTHER:PTN002517083
PomBase:SPBC25B2.02c
PomBase:SPCC737.09c
SGD:S000004916
TAIR:locus:2041434
UniProtKB:A0A1D8PKI5
UniProtKB:P21439
UniProtKB:Q03519
UniProtKB:Q9NP58
UniProtKB:Q9NP78
ZFIN:ZDB-GENE-080204-52

F

Seeded From UniProt

complete

protected

part_of

GO:0016021

integral component of membrane

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10613
EcoGene:EG11405
FB:FBgn0004513
MGI:MGI:1924956
PANTHER:PTN002517083
PomBase:SPCC737.09c
RGD:3817
RGD:3818
UniProtKB:Q03518
UniProtKB:Q03519
UniProtKB:Q2M3G0
UniProtKB:Q8IDT6
UniProtKB:Q9NP58
UniProtKB:Q9NP78
UniProtKB:Q9NRK6
WB:WBGene00001815

C

Seeded From UniProt

complete

protected

part_of

GO:0005886

plasma membrane

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0004513
MGI:MGI:1924956
MGI:MGI:97569
MGI:MGI:97570
PANTHER:PTN002795061
RGD:3318
RGD:619930
RGD:620248
UniProtKB:P08183
UniProtKB:P21439
UniProtKB:Q2M3G0
WB:WBGene00003995

C

Seeded From UniProt

complete

protected

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003439
InterPro:IPR011527
InterPro:IPR017871
InterPro:IPR036640

F

Seeded From UniProt

complete

protected

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011527
InterPro:IPR036640

C

Seeded From UniProt

complete

protected

enables

GO:0016887

ATPase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003439
InterPro:IPR017871

F

Seeded From UniProt

complete

protected

enables

GO:0042626

ATPase activity, coupled to transmembrane movement of substances

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011527

F

Seeded From UniProt

complete

protected

involved_in

GO:0055085

transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011527

P

Seeded From UniProt

complete

protected

enables

GO:0042626

ATPase activity, coupled to transmembrane movement of substances

PMID:3022150

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

protected

involved_in

GO:0042493

response to drug

PMID:3022150

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0016021

integral component of membrane

PMID:3768958

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

protected

part_of

GO:0016020

membrane

PMID:3022150

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

protected

enables

GO:0005524

ATP binding

PMID:3768958

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

protected

enables

GO:0005215

transporter activity

PMID:3022150

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

protected

involved_in

GO:0055085

transmembrane transport

Reactome:R-HSA-382556

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0005886

plasma membrane

Reactome:R-HSA-1467457

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

protected

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

protected

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

protected

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

protected

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

protected

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete




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