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PMID:20657843
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Citation |
Goswami, C, Kuhn, J, Heppenstall, PA and Hucho, T (2010) Importance of non-selective cation channel TRPV4 interaction with cytoskeleton and their reciprocal regulations in cultured cells. PLoS ONE 5:e11654 |
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Abstract |
TRPV4 and the cellular cytoskeleton have each been reported to influence cellular mechanosensitive processes as well as the development of mechanical hyperalgesia. If and how TRPV4 interacts with the microtubule and actin cytoskeleton at a molecular and functional level is not known. |
Links |
PubMed PMC2906515 Online version:10.1371/journal.pone.0011654 |
Keywords |
Actins/metabolism; Animals; Cell Line, Tumor; Cytoskeleton/metabolism; Immunohistochemistry; Immunoprecipitation; Male; Mice; Neurofilament Proteins/metabolism; Protein Binding; Rats; TRPV Cation Channels/metabolism; Tubulin/metabolism |
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