GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
TableEdit
PMID:14711369
You don't have sufficient rights on this wiki to edit tables. Perhaps you need to log in. Changes you make in the Table editor will not be saved back to the wiki
See Help for Help on this wiki. See the documentation for how to use the table editor
| Citation |
Borrelly, GP, Blindauer, CA, Schmid, R, Butler, CS, Cooper, CE, Harvey, I, Sadler, PJ and Robinson, NJ (2004) A novel copper site in a cyanobacterial metallochaperone. Biochem. J. 378:293-7 |
|---|---|
| Abstract |
The thylakoid lumen of the cyanobacterium Synechocystis PCC 6803 is supplied with copper via two copper-transporting ATPases and a metallochaperone intermediary. We show that the copper site of this metallochaperone is unusual and consists of two cysteine residues and a histidine imidazole located on structurally dynamic loops. Substitution of this histidine residue enhances bacterial two-hybrid interaction with the cytosolic copper exporter, but not the copper importer, suggesting that the interacting surfaces are distinct, with implications for metal transfer. |
| Links |
PubMed PMC1223992 Online version:10.1042/BJ20031669 |
| Keywords |
ATP-Binding Cassette Transporters; Adenosine Triphosphatases/metabolism; Amino Acid Substitution; Bacterial Proteins/metabolism; Binding Sites; Carrier Proteins/metabolism; Cation Transport Proteins/chemistry; Cation Transport Proteins/genetics; Cation Transport Proteins/metabolism; Copper/analysis; Copper/chemistry; Copper/metabolism; Cyanobacteria/chemistry; Cyanobacteria/metabolism; Cysteine/analysis; Ferredoxins/chemistry; Histidine/analysis; Histidine/chemistry; Ion Transport; Models, Molecular; Protein Folding |
| public |
| Cancel |
