GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

TableEdit

Jump to: navigation, search

PMID:18394898

You don't have sufficient rights on this wiki to edit tables. Perhaps you need to log in. Changes you make in the Table editor will not be saved back to the wiki

See Help for Help on this wiki. See the documentation for how to use the table editor

Citation

Pujol, N, Cypowyj, S, Ziegler, K, Millet, A, Astrain, A, Goncharov, A, Jin, Y, Chisholm, AD and Ewbank, JJ (2008) Distinct innate immune responses to infection and wounding in the C. elegans epidermis. Curr. Biol. 18:481-9

Abstract

In many animals, the epidermis is in permanent contact with the environment and represents a first line of defense against pathogens and injury. Infection of the nematode Caenorhabditis elegans by the natural fungal pathogen Drechmeria coniospora induces the expression in the epidermis of antimicrobial peptide (AMP) genes such as nlp-29. Here, we tested the hypothesis that injury might also alter AMP gene expression and sought to characterize the mechanisms that regulate the innate immune response.

Links

PubMed PMC2394561 Online version:10.1016/j.cub.2008.02.079

Keywords

Amino Acid Sequence; Animals; Antimicrobial Cationic Peptides/genetics; Antimicrobial Cationic Peptides/metabolism; Caenorhabditis elegans/genetics; Caenorhabditis elegans/immunology; Caenorhabditis elegans/metabolism; Caenorhabditis elegans Proteins/metabolism; Epidermis/immunology; Immunity, Innate/physiology; Infection/immunology; Infection/metabolism; Molecular Sequence Data; Neuropeptides/metabolism; Protein Kinases/metabolism; Signal Transduction/physiology; Up-Regulation; Wound Healing/physiology; p38 Mitogen-Activated Protein Kinases/metabolism

public



Cancel