GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
TableEdit
PMID:17078885
You don't have sufficient rights on this wiki to edit tables. Perhaps you need to log in. Changes you make in the Table editor will not be saved back to the wiki
See Help for Help on this wiki. See the documentation for how to use the table editor
| Citation |
Wang, J, Nagy, A, Larsson, J, Dudas, M, Sucov, HM and Kaartinen, V (2006) Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects. BMC Dev. Biol. 6:51 |
|---|---|
| Abstract |
Congenital cardiovascular diseases are the most common form of birth defects in humans. A substantial portion of these defects has been associated with inappropriate induction, migration, differentiation and patterning of pluripotent cardiac neural crest stem cells. While TGF-beta-superfamily signaling has been strongly implicated in neural crest cell development, the detailed molecular signaling mechanisms in vivo are still poorly understood. |
| Links |
PubMed PMC1635039 Online version:10.1186/1471-213X-6-51 |
| Keywords |
Activin Receptors, Type I/deficiency; Activin Receptors, Type I/genetics; Activin Receptors, Type I/physiology; Animals; Aorta/abnormalities; Aorta/embryology; Apoptosis/genetics; Branchial Region/abnormalities; Branchial Region/embryology; Cell Movement/genetics; Female; Heart Defects, Congenital/embryology; Heart Defects, Congenital/genetics; Mice; Mice, Knockout; Mice, Transgenic; Neural Crest/embryology; Neural Crest/pathology; Protein-Serine-Threonine Kinases; Receptors, Transforming Growth Factor beta/deficiency; Receptors, Transforming Growth Factor beta/genetics; Receptors, Transforming Growth Factor beta/physiology; Signal Transduction/genetics |
| public |
| Cancel |
