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Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

protected

enables

GO:0051087

chaperone binding

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002567658
RGD:69062

F

Seeded From UniProt

complete

protected

involved_in

GO:0045930

negative regulation of mitotic cell cycle

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000814137
UniProtKB:P46527
ZFIN:ZDB-GENE-040123-1

P

Seeded From UniProt

complete

protected

involved_in

GO:0045736

negative regulation of cyclin-dependent protein serine/threonine kinase activity

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:104565
PANTHER:PTN000814137
RGD:69062
UniProtKB:P46527

P

Seeded From UniProt

complete

protected

involved_in

GO:0042326

negative regulation of phosphorylation

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000814137
UniProtKB:P46527

P

Seeded From UniProt

complete

protected

involved_in

GO:0008285

negative regulation of cell population proliferation

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:104565
PANTHER:PTN002567658
RGD:69062
UniProtKB:P46527

P

Seeded From UniProt

complete

protected

involved_in

GO:0007050

cell cycle arrest

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:104565
PANTHER:PTN002567658
UniProtKB:P46527

P

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:104565
PANTHER:PTN002567658
RGD:69062
UniProtKB:P46527

C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:104565
PANTHER:PTN002567658
RGD:69062
UniProtKB:P46527

C

Seeded From UniProt

complete

protected

enables

GO:0004861

cyclin-dependent protein serine/threonine kinase inhibitor activity

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:104565
PANTHER:PTN002567658
UniProtKB:P46527

F

Seeded From UniProt

complete

protected

involved_in

GO:0000082

G1/S transition of mitotic cell cycle

PMID:21873635

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:104565
PANTHER:PTN002567658
UniProtKB:P46527

P

Seeded From UniProt

complete

protected

involved_in

GO:1905179

negative regulation of cardiac muscle tissue regeneration

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

P

Seeded From UniProt

complete

protected

involved_in

GO:1902746

regulation of lens fiber cell differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

P

Seeded From UniProt

complete

protected

involved_in

GO:0071850

mitotic cell cycle arrest

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

P

Seeded From UniProt

complete

protected

involved_in

GO:0071407

cellular response to organic cyclic compound

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

P

Seeded From UniProt

complete

protected

involved_in

GO:0071236

cellular response to antibiotic

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

P

Seeded From UniProt

complete

protected

involved_in

GO:0060770

negative regulation of epithelial cell proliferation involved in prostate gland development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

P

Seeded From UniProt

complete

protected

involved_in

GO:0051271

negative regulation of cellular component movement

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

P

Seeded From UniProt

complete

protected

involved_in

GO:0050680

negative regulation of epithelial cell proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

P

Seeded From UniProt

complete

protected

involved_in

GO:0048839

inner ear development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

P

Seeded From UniProt

complete

protected

involved_in

GO:0045736

negative regulation of cyclin-dependent protein serine/threonine kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

P

Seeded From UniProt

complete

protected

involved_in

GO:0043066

negative regulation of apoptotic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

P

Seeded From UniProt

complete

protected

involved_in

GO:0031116

positive regulation of microtubule polymerization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

P

Seeded From UniProt

complete

protected

enables

GO:0030332

cyclin binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

F

Seeded From UniProt

complete

protected

involved_in

GO:0008285

negative regulation of cell population proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

P

Seeded From UniProt

complete

protected

involved_in

GO:0008284

positive regulation of cell population proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

P

Seeded From UniProt

complete

protected

involved_in

GO:0007605

sensory perception of sound

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

P

Seeded From UniProt

complete

protected

involved_in

GO:0007507

heart development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

P

Seeded From UniProt

complete

protected

involved_in

GO:0007219

Notch signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

P

Seeded From UniProt

complete

protected

involved_in

GO:0007096

regulation of exit from mitosis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

P

Seeded From UniProt

complete

protected

involved_in

GO:0007050

cell cycle arrest

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

P

Seeded From UniProt

complete

protected

involved_in

GO:0006813

potassium ion transport

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

P

Seeded From UniProt

complete

protected

part_of

GO:0005829

cytosol

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

C

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

C

Seeded From UniProt

complete

protected

enables

GO:0004861

cyclin-dependent protein serine/threonine kinase inhibitor activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

F

Seeded From UniProt

complete

protected

involved_in

GO:0000082

G1/S transition of mitotic cell cycle

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46414
ensembl:ENSMUSP00000065832

P

Seeded From UniProt

complete

protected

involved_in

GO:1904706

negative regulation of vascular smooth muscle cell proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

P

Seeded From UniProt

complete

protected

involved_in

GO:1904030

negative regulation of cyclin-dependent protein kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

P

Seeded From UniProt

complete

protected

involved_in

GO:0071850

mitotic cell cycle arrest

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

P

Seeded From UniProt

complete

protected

involved_in

GO:0071285

cellular response to lithium ion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

P

Seeded From UniProt

complete

protected

involved_in

GO:0048102

autophagic cell death

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

P

Seeded From UniProt

complete

protected

involved_in

GO:0045930

negative regulation of mitotic cell cycle

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

P

Seeded From UniProt

complete

protected

involved_in

GO:0045892

negative regulation of transcription, DNA-templated

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

P

Seeded From UniProt

complete

protected

involved_in

GO:0045786

negative regulation of cell cycle

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

P

Seeded From UniProt

complete

protected

involved_in

GO:0045736

negative regulation of cyclin-dependent protein serine/threonine kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

P

Seeded From UniProt

complete

protected

involved_in

GO:0045732

positive regulation of protein catabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

P

Seeded From UniProt

complete

protected

enables

GO:0044877

protein-containing complex binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

F

Seeded From UniProt

complete

protected

part_of

GO:0043231

intracellular membrane-bounded organelle

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

C

Seeded From UniProt

complete

protected

involved_in

GO:0042326

negative regulation of phosphorylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

P

Seeded From UniProt

complete

protected

involved_in

GO:0033673

negative regulation of kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

P

Seeded From UniProt

complete

protected

part_of

GO:0031464

Cul4A-RING E3 ubiquitin ligase complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

C

Seeded From UniProt

complete

protected

enables

GO:0030332

cyclin binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

F

Seeded From UniProt

complete

protected

involved_in

GO:0030308

negative regulation of cell growth

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

P

Seeded From UniProt

complete

protected

enables

GO:0019903

protein phosphatase binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

F

Seeded From UniProt

complete

protected

enables

GO:0019901

protein kinase binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

F

Seeded From UniProt

complete

protected

involved_in

GO:0010942

positive regulation of cell death

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

P

Seeded From UniProt

complete

protected

involved_in

GO:0008285

negative regulation of cell population proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

P

Seeded From UniProt

complete

protected

involved_in

GO:0007050

cell cycle arrest

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

P

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

C

Seeded From UniProt

complete

protected

enables

GO:0004861

cyclin-dependent protein serine/threonine kinase inhibitor activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

F

Seeded From UniProt

complete

protected

enables

GO:0004860

protein kinase inhibitor activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

F

Seeded From UniProt

complete

protected

involved_in

GO:0000082

G1/S transition of mitotic cell cycle

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P46527
ensembl:ENSP00000228872

P

Seeded From UniProt

complete

protected

part_of

GO:0043231

intracellular membrane-bounded organelle

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6I9V6
ensembl:ENSP00000228872

C

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6I9V6
ensembl:ENSP00000228872

C

Seeded From UniProt

complete

protected

enables

GO:0004861

cyclin-dependent protein serine/threonine kinase inhibitor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003175
InterPro:IPR029843

F

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003175
InterPro:IPR029843

C

Seeded From UniProt

complete

protected

part_of

GO:0005737

cytoplasm

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029843

C

Seeded From UniProt

complete

protected

involved_in

GO:0007050

cell cycle arrest

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003175

P

Seeded From UniProt

complete

protected

involved_in

GO:0042127

regulation of cell population proliferation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029843

P

Seeded From UniProt

complete

protected

involved_in

GO:0016310

phosphorylation

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

protected

enables

GO:0016301

kinase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete



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