GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
TableEdit
PMID:28012171
You don't have sufficient rights on this wiki to edit tables. Perhaps you need to log in. Changes you make in the Table editor will not be saved back to the wiki
See Help for Help on this wiki. See the documentation for how to use the table editor
| Citation |
Ito, N, Sakai, A, Miyake, N, Maruyama, M, Iwasaki, H, Miyake, K, Okada, T, Sakamoto, A and Suzuki, H (2017) miR-15b mediates oxaliplatin-induced chronic neuropathic pain through BACE1 down-regulation. Br. J. Pharmacol. 174:386-395 |
|---|---|
| Abstract |
Although oxaliplatin is an effective anti-cancer platinum compound, it can cause painful chronic neuropathy, and its molecular mechanisms are poorly understood. MicroRNAs (miRNAs) are small non-coding RNAs that negatively regulate gene expression in a sequence-specific manner. Although miRNAs have been increasingly recognized as important modulators in a variety of pain conditions, their involvement in chemotherapy-induced neuropathic pain is unknown. |
| Links |
PubMed PMC5301044 Online version:10.1111/bph.13698 |
| Keywords |
Amyloid Precursor Protein Secretases/genetics; Animals; Antineoplastic Agents/toxicity; Aspartic Acid Endopeptidases/genetics; Down-Regulation/genetics; Ganglia, Spinal/metabolism; Injections, Intraperitoneal; Male; MicroRNAs/genetics; Neuralgia/chemically induced; Neuralgia/genetics; Neurons/metabolism; Organoplatinum Compounds/toxicity; Oxaliplatin; Rats; Rats, Sprague-Dawley |
| public |
| Cancel |
