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TableEdit
HUMAN:TCP4
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| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status | |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
protected |
part_of |
GO:0070062 |
extracellular exosome |
PMID:20458337 |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
part_of:(CL:0000639) |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0003723 |
RNA binding |
PMID:22681889 |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | ||
|
public |
GO:0051053 |
negative regulation of DNA metabolic process |
PMID:28369605 |
ECO:0000314 |
P |
Paper’s Protein Name: “Human homolog of Sub1, variously referred to as hSub1, p15 or PC4.” PC4 is primarily used. Uniprot’s Protein Name: Activated RNA polymerase II transcriptional coactivator p15. Organism: Homo sapiens. Notes: Figures 2B-E are all applicable, but I will primarily use 2B. The paper states that “the ectopic expression of Sub1 or PC4 reduced the rate of recombination for the pTET-lys2-GTOP construct by 9.6- and 10.3-fold, respectively, thereby resulting in the rates of recombination that are significantly lower than in top1Δ single deletion strains (Figure 2B).” Thus, PC4 seems to be linked to down-regulation of DNA recombination. The procedures of this experiment involve transforming yeast strains with a “PC4 expression vector,” so the evidence code should be IDA. |
complete | ||||
|
protected |
enables |
GO:0003723 |
RNA binding |
PMID:22658674 |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:0006357 |
regulation of transcription by RNA polymerase II |
PMID:8062391 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
part_of |
GO:0005667 |
transcription factor complex |
PMID:8062391 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
protected |
enables |
GO:0003713 |
transcription coactivator activity |
PMID:8062391 |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | ||
|
protected |
enables |
GO:0003697 |
single-stranded DNA binding |
PMID:8062391 |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:0060261 |
positive regulation of transcription initiation from RNA polymerase II promoter |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000325022 |
P |
Seeded From UniProt |
complete | |
|
protected |
part_of |
GO:0005667 |
transcription factor complex |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000325022 |
C |
Seeded From UniProt |
complete | |
|
protected |
part_of |
GO:0005634 |
nucleus |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0015299 |
C |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0003713 |
transcription coactivator activity |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000325022 |
F |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0042802 |
identical protein binding |
PMID:25416956 |
ECO:0000353 |
physical interaction evidence used in manual assertion |
UniProtKB:P53999 |
F |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0042802 |
identical protein binding |
PMID:16415882 |
ECO:0000353 |
physical interaction evidence used in manual assertion |
UniProtKB:P53999 |
F |
Seeded From UniProt |
complete | |
|
protected |
part_of |
GO:0005730 |
nucleolus |
GO_REF:0000052 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
protected |
part_of |
GO:0005634 |
nucleus |
GO_REF:0000052 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
protected |
enables |
GO:1990837 |
sequence-specific double-stranded DNA binding |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P11031 |
F |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0060395 |
SMAD protein signal transduction |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P11031 |
P |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0001228 |
DNA-binding transcription activator activity, RNA polymerase II-specific |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P11031 |
F |
Seeded From UniProt |
complete | |
|
protected |
part_of |
GO:0005634 |
nucleus |
GO_REF:0000107 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q63396 |
C |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0003677 |
DNA binding |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR003173 |
F |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR003173 |
P |
Seeded From UniProt |
complete | |
|
protected |
part_of |
GO:0005634 |
nucleus |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0539 |
C |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0003677 |
DNA binding |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0238 |
F |
Seeded From UniProt |
complete |
| Cancel |
