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TableEdit
HUMAN:ASXL3
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Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status | |
---|---|---|---|---|---|---|---|---|---|---|---|
public |
GO:0051055 |
negative regulation of lipid biosynthetic process |
PMID:25450400 |
ECO:0000314 |
P |
As shown in Fig. 4E, ASXL3 overexpression reduced intracellular lipid deposition. This data suggests that ASXL3 negatively regulates lipogenesis by repressing the transcriptional activity of LXRα, a key mediator of lipogenesis in the liver. |
complete | ||||
protected |
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2684063 |
P |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0042975 |
peroxisome proliferator activated receptor binding |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2684063 |
F |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0035517 |
PR-DUB complex |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0261823 |
C |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0009887 |
animal organ morphogenesis |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2684063 |
P |
Seeded From UniProt |
complete | |
protected |
colocalizes_with |
GO:0005634 |
nucleus |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0261823 |
C |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0003682 |
chromatin binding |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0261823 |
F |
Seeded From UniProt |
complete | |
protected |
colocalizes_with |
GO:0000790 |
nuclear chromatin |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1922552 |
C |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0003677 |
DNA binding |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR026905 |
F |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0006351 |
transcription, DNA-templated |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR007759 |
P |
Seeded From UniProt |
complete | |
protected |
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR007759 |
P |
Seeded From UniProt |
complete | |
protected |
enables |
GO:0046872 |
metal ion binding |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0479 |
F |
Seeded From UniProt |
complete | |
protected |
part_of |
GO:0005634 |
nucleus |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0539 |
C |
Seeded From UniProt |
complete |
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