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TableEdit
STRAJ:THCL
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| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status | |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
public |
GO:0006917 |
induction of apoptosis |
PMID:18583930 |
ECO:0000270 |
P |
Figure 1 shows a decrease in percent of live melanoma cells as concentration of thiostrepton increases, suggesting an induction of apoptosis as supported by the article. |
complete | ||||
|
public |
GO:0045900 |
negative regulation of translational elongation |
PMID:18406324 |
ECO:0000315 |
P |
Refer to Figure 3, which shows the structures and interactions of Thiostrepton with the ribosome. This interaction has been proven to inhibit elongation by interfering with EF-G processes. |
complete | ||||
|
public |
GO:0008539 |
proteasome inhibitor activity |
PMID:19672316 |
ECO:0000314 |
F |
See Figure 1C. The results show that Thiostrepton, when compared to No Drug, decreases proteasome activity. |
complete | ||||
|
protected |
involved_in |
GO:0042742 |
defense response to bacterium |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0044 |
P |
Seeded From UniProt |
complete | |
|
protected |
part_of |
GO:0005576 |
extracellular region |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0964 |
C |
Seeded From UniProt |
complete |
| Cancel |
