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HUMAN:GAB1

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Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

protected

involved_in

GO:0038089

positive regulation of cell migration by vascular endothelial growth factor signaling pathway

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9QYY0

P

occurs_in:(CL:0002544)

Seeded From UniProt

complete

protected

involved_in

GO:0031532

actin cytoskeleton reorganization

PMID:17178724

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(CL:2000008)

Seeded From UniProt

complete

protected

involved_in

GO:0001525

angiogenesis

PMID:17178724

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(CL:2000008)

Seeded From UniProt

complete

protected

involved_in

GO:0090668

endothelial cell chemotaxis to vascular endothelial growth factor

PMID:17178724

ECO:0000315

mutant phenotype evidence used in manual assertion

P

results_in_movement_of:(CL:2000008)

Seeded From UniProt

complete

protected

involved_in

GO:0038084

vascular endothelial growth factor signaling pathway

PMID:17178724

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(CL:2000008)

Seeded From UniProt

complete

protected

involved_in

GO:0045766

positive regulation of angiogenesis

PMID:25217442

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(CL:0000071)

Seeded From UniProt

complete

protected

involved_in

GO:0035728

response to hepatocyte growth factor

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:A0A0G2JZD5
ensembl:ENSRNOP00000071006

P

Seeded From UniProt

complete

protected

involved_in

GO:0008286

insulin receptor signaling pathway

PMID:8596638

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0007173

epidermal growth factor receptor signaling pathway

PMID:8596638
Reactome:R-HSA-177929

ECO:0000304

author statement supported by traceable reference used in manual assertion


P

Seeded From UniProt

complete

protected

enables

GO:0005070

SH3/SH2 adaptor activity

PMID:8596638

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

protected

involved_in

GO:0051897

positive regulation of protein kinase B signaling

Reactome:R-HSA-2316434

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0038128

ERBB2 signaling pathway

Reactome:R-HSA-1227986

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

public

GO:2000147

positive regulation of cell motility

PMID:20506405

ECO:0000314

P

Figure 2. Gab1 constitutively enhances migration and stimulates adhesion of 32D/Met cells. A: The migration of 32D/Met cells (open bars), 32D/Met/Gab1clone 1W5 (black bars), and 32D/Met/Gab1 clone 1W3 (gray bars) was measured using modified Boyden chambers. NK1 concentrations are indicated on the X-axis. Results are expressed as number of migrating cells/ml of medium in the bottom chamber and are representative of three or more experiments.

complete

protected

involved_in

GO:0014068

positive regulation of phosphatidylinositol 3-kinase signaling

Reactome:R-HSA-9027276

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0007411

axon guidance

Reactome:R-HSA-422475

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0005829

cytosol

Reactome:R-HSA-9027281
Reactome:R-HSA-9027275
Reactome:R-HSA-9027273
Reactome:R-HSA-9021627
Reactome:R-HSA-8875661
Reactome:R-HSA-8875659
Reactome:R-HSA-8875591
Reactome:R-HSA-8875576
Reactome:R-HSA-8875568
Reactome:R-HSA-8875558
Reactome:R-HSA-8875540
Reactome:R-HSA-8865994
Reactome:R-HSA-8855508
Reactome:R-HSA-8854905
Reactome:R-HSA-8854897
Reactome:R-HSA-8853774
Reactome:R-HSA-8853323
Reactome:R-HSA-8853316
Reactome:R-HSA-8853308
Reactome:R-HSA-8852019
Reactome:R-HSA-8851954
Reactome:R-HSA-8851933
Reactome:R-HSA-8851919
Reactome:R-HSA-8851908
Reactome:R-HSA-5655323
Reactome:R-HSA-5655320
Reactome:R-HSA-5655315
Reactome:R-HSA-5655290
Reactome:R-HSA-5655289
Reactome:R-HSA-5655285
Reactome:R-HSA-5655263
Reactome:R-HSA-5655252
Reactome:R-HSA-5655248
Reactome:R-HSA-5655245
Reactome:R-HSA-5655240
Reactome:R-HSA-5655235
Reactome:R-HSA-5654717
Reactome:R-HSA-5654714
Reactome:R-HSA-5654709
Reactome:R-HSA-5654705
Reactome:R-HSA-5654701
Reactome:R-HSA-5654697
Reactome:R-HSA-5654692
Reactome:R-HSA-5654690
Reactome:R-HSA-5654669
Reactome:R-HSA-5654667
Reactome:R-HSA-5654662
Reactome:R-HSA-5654659
Reactome:R-HSA-5654643
Reactome:R-HSA-5654641
Reactome:R-HSA-5654640
Reactome:R-HSA-5654637
Reactome:R-HSA-5654622
Reactome:R-HSA-5654620
Reactome:R-HSA-5654614
Reactome:R-HSA-5654612
Reactome:R-HSA-5654596
Reactome:R-HSA-5654594
Reactome:R-HSA-5654592
Reactome:R-HSA-5654591
Reactome:R-HSA-5637801
Reactome:R-HSA-5637765
Reactome:R-HSA-5637764
Reactome:R-HSA-2400009
Reactome:R-HSA-2316434
Reactome:R-HSA-179467
Reactome:R-HSA-177944
Reactome:R-HSA-177941
Reactome:R-HSA-177939
Reactome:R-HSA-177935
Reactome:R-HSA-177931
Reactome:R-HSA-177930
Reactome:R-HSA-177927
Reactome:R-HSA-177926
Reactome:R-HSA-177924
Reactome:R-HSA-177923
Reactome:R-HSA-177920
Reactome:R-HSA-1306965
Reactome:R-HSA-1306963
Reactome:R-HSA-1306957
Reactome:R-HSA-1226016
Reactome:R-HSA-1226014
Reactome:R-HSA-1226012
Reactome:R-HSA-109699

ECO:0000304

author statement supported by traceable reference used in manual assertion




















































































C

Seeded From UniProt

complete




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