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YEAST:FOB1

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Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

public

GO:0007580

extrachromosomal circular DNA accumulation involved in cell aging

PMID:10521401

ECO:0000315

P

Figure 4.Accumulation of ERCs occurs more rapidly in a sir2 mutant than in wild-type mother cells when the cell is FOB1 dependent.Mutation of fob1 in sir2D hmlD mother cells decreases ERC accumulation below levels observed in wild-type cells.

complete

public

GO:0007569

cell aging

PMID:10521401

ECO:0000315

P

Figure 6.shows that Mutation of fob1 suppresses the life span defect of a sir2 mutant.

complete

protected

involved_in

GO:0045911

positive regulation of DNA recombination

PMID:25822194

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0090342

regulation of cell aging

PMID:25822194

ECO:0000316

genetic interaction evidence used in manual assertion

SGD:S000004500

P

Seeded From UniProt

complete

protected

involved_in

GO:0090342

regulation of cell aging

PMID:25822194

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0070550

rDNA condensation

PMID:18923139

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0007059

chromosome segregation

PMID:16769819

ECO:0000316

genetic interaction evidence used in manual assertion

SGD:S000001924

P

Seeded From UniProt

complete

protected

enables

GO:0043110

rDNA spacer replication fork barrier binding

PMID:14645529

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

protected

involved_in

GO:0043007

maintenance of rDNA

PMID:23593017

ECO:0000316

genetic interaction evidence used in manual assertion

SGD:S000003925

P

Seeded From UniProt

complete

protected

involved_in

GO:0034503

protein localization to nucleolar rDNA repeats

PMID:19362534

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0033553

rDNA heterochromatin

PMID:22362748

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0008156

negative regulation of DNA replication

PMID:14645529

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0007580

extrachromosomal circular DNA accumulation involved in cell aging

PMID:10230397

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0006310

DNA recombination

PMID:9078378

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

part_of

GO:0005730

nucleolus

PMID:10230397

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

protected

involved_in

GO:0001302

replicative cell aging

PMID:15722108

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0000183

chromatin silencing at rDNA

PMID:12923057

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

protected

enables

GO:0043110

rDNA spacer replication fork barrier binding

PMID:26951198

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

protected

involved_in

GO:0000183

chromatin silencing at rDNA

PMID:26951198

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0031582

replication fork arrest at rDNA repeats

PMID:26951198

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0006325

chromatin organization

PMID:26951198

ECO:0000316

genetic interaction evidence used in manual assertion

SGD:S000002200

P

Seeded From UniProt

complete

protected

involved_in

GO:0090579

dsDNA loop formation

PMID:26951198

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

protected

involved_in

GO:0006310

DNA recombination

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0233

P

Seeded From UniProt

complete

protected

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

protected

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

protected

involved_in

GO:0006260

DNA replication

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0235

P

Seeded From UniProt

complete

protected

part_of

GO:0005634

nucleus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539

C

Seeded From UniProt

complete

protected

part_of

GO:0005730

nucleolus

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0188

C

Seeded From UniProt

complete




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