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TableEdit
HUMAN:UBR5
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| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status | |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
public |
GO:0005515 |
protein binding |
PMID:21118991 |
ECO:0000021 |
UniProtKB:p49841
|
F |
Fig 1A, 1B – Co-immunoprecipitation between GSK-3 and EDD Fig 1E – Pulldown GSK-3β bound EDD |
complete | |||
|
public |
GO:0000209 |
protein polyubiquitination |
PMID:21118991 |
ECO:0000314 |
P |
Fig. 5B EDD was silenced in HEK293T cells expressing HA-ubiquitin causing reduced ubiqutination of endogenous β-catenin, indicating a specific ubiquitination of β-catenin by EDD |
complete | ||||
|
public |
GO:0005634 |
nucleus |
PMID:21118991 |
ECO:0000314 |
C |
Fig 2A, B shows EDD in nucleus. Nucleus marked by DAPI in B. |
complete | ||||
|
protected |
part_of |
GO:0016020 |
membrane |
PMID:19946888 |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:0090263 |
positive regulation of canonical Wnt signaling pathway |
PMID:21118991 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
enables |
GO:0034450 |
ubiquitin-ubiquitin ligase activity |
PMID:21118991 |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
has_direct_input:(UniProtKB:P35222) |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0042307 |
positive regulation of protein import into nucleus |
PMID:21118991 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
has_regulation_target:(UniProtKB:P49841) |
Seeded From UniProt |
complete | |
|
protected |
part_of |
GO:0005634 |
nucleus |
PMID:21118991 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:0000209 |
protein polyubiquitination |
PMID:21118991 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:0050847 |
progesterone receptor signaling pathway |
PMID:12011095 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:0006974 |
cellular response to DNA damage stimulus |
PMID:12011095 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
part_of |
GO:0005634 |
nucleus |
PMID:12011095 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:2000780 |
negative regulation of double-strand break repair |
PMID:22884692 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:1901315 |
negative regulation of histone H2A K63-linked ubiquitination |
PMID:22884692 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:0006974 |
cellular response to DNA damage stimulus |
PMID:22884692 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:1901315 |
negative regulation of histone H2A K63-linked ubiquitination |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000883184 |
P |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0006974 |
cellular response to DNA damage stimulus |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000134821 |
P |
Seeded From UniProt |
complete | |
|
protected |
part_of |
GO:0005634 |
nucleus |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0002431 |
C |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0000209 |
protein polyubiquitination |
PMID:21873635 |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000883184 |
P |
Seeded From UniProt |
complete | |
|
protected |
part_of |
GO:0048471 |
perinuclear region of cytoplasm |
PMID:18076571 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
protected |
part_of |
GO:0032991 |
protein-containing complex |
PMID:18076571 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:0010628 |
positive regulation of gene expression |
PMID:18076571 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
part_of |
GO:0005829 |
cytosol |
GO_REF:0000052 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
protected |
part_of |
GO:0005654 |
nucleoplasm |
GO_REF:0000052 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:0000209 |
protein polyubiquitination |
PMID:28689657 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
involved_in |
GO:0070936 |
protein K48-linked ubiquitination |
PMID:28689657 |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
part_of |
GO:0005634 |
nucleus |
PMID:28689657 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
protected |
enables |
GO:0061630 |
ubiquitin protein ligase activity |
PMID:28689657 |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
has_direct_input:(UniProtKB:Q04726) |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0090263 |
positive regulation of canonical Wnt signaling pathway |
PMID:28689657 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
protected |
enables |
GO:0003723 |
RNA binding |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR002004 |
F |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0004842 |
ubiquitin-protein transferase activity |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000569 |
F |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0008270 |
zinc ion binding |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR003126 |
F |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0043130 |
ubiquitin binding |
GO_REF:0000002 |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR024725 |
F |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0006281 |
DNA repair |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0234 |
P |
Seeded From UniProt |
complete | |
|
protected |
part_of |
GO:0005634 |
nucleus |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0539 |
C |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0006974 |
cellular response to DNA damage stimulus |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0227 |
P |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0016740 |
transferase activity |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0808 |
F |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0016032 |
viral process |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0945 |
P |
Seeded From UniProt |
complete | |
|
protected |
enables |
GO:0046872 |
metal ion binding |
GO_REF:0000037 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0479 |
F |
Seeded From UniProt |
complete | |
|
protected |
involved_in |
GO:0016567 |
protein ubiquitination |
GO_REF:0000041 |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00143 |
P |
Seeded From UniProt |
complete |
| Cancel |
