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YERPS:YOPB

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Species (Taxon ID) Yersinia pseudotuberculosis serotype I (strain IP32953). (273123)
Gene Name(s) yopB
Protein Name(s) Protein YopB
External Links
UniProt Q06114
EMBL L06215
BX936399
RefSeq WP_011191382.1
YP_068464.1
STRING 273123.pYV0055
TCDB 1.C.36.2.1
EnsemblBacteria CAF25398
GeneID 2952948
KEGG yps:pYV0055
PATRIC 18637866
eggNOG COG5613
HOGENOM HOG000219600
OMA AKIFGWI
OrthoDB EOG6GTZGD
BioCyc YPSE273123:GI1M-4151-MONOMER
Proteomes UP000001011
GO GO:0016021
GO:0005886
GO:0009405
InterPro IPR006972
Pfam PF04888

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0042536

negative regulation of tumor necrosis factor biosynthetic process

PMID:9535085[1]

ECO:0000335

P

occurs_in:CL:0000235

CL:0000235 occurs in human macrophages. Figure 1B shows J774A.1 macrophages were infected with Yersinia pseudotuberculosis strains both able and unable to secrete full-length translocon YopB for 1 hour. Levels of TNF-alpha in media were quantified, with YopB mutants consistently producing twofold more TNF-alpha. Yersinia pseudotuberculosis

A0A0N9NJG3 should be the protein ID. This is described as an Uncharacterized protein, I chose this protein designation because there is no YopB for Yersinia pseudotuberculosis.

complete
CACAO 13638

involved_in

GO:0009405

pathogenesis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006972

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0843

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Palmer, LE et al. (1998) YopJ of Yersinia pseudotuberculosis is required for the inhibition of macrophage TNF-alpha production and downregulation of the MAP kinases p38 and JNK. Mol. Microbiol. 27 953-65 PubMed GONUTS page