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YERPS:YOPB
Contents
| Species (Taxon ID) | Yersinia pseudotuberculosis serotype I (strain IP32953). (273123) | |
| Gene Name(s) | yopB | |
| Protein Name(s) | Protein YopB | |
| External Links | ||
| UniProt | Q06114 | |
| EMBL | L06215 BX936399 | |
| RefSeq | WP_011191382.1 YP_068464.1 | |
| STRING | 273123.pYV0055 | |
| TCDB | 1.C.36.2.1 | |
| EnsemblBacteria | CAF25398 | |
| GeneID | 2952948 | |
| KEGG | yps:pYV0055 | |
| PATRIC | 18637866 | |
| eggNOG | COG5613 | |
| HOGENOM | HOG000219600 | |
| OMA | AKIFGWI | |
| OrthoDB | EOG6GTZGD | |
| BioCyc | YPSE273123:GI1M-4151-MONOMER | |
| Proteomes | UP000001011 | |
| GO | GO:0016021 GO:0005886 GO:0009405 | |
| InterPro | IPR006972 | |
| Pfam | PF04888 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0042536 |
negative regulation of tumor necrosis factor biosynthetic process |
ECO:0000335 |
P |
occurs_in:CL:0000235 |
CL:0000235 occurs in human macrophages. Figure 1B shows J774A.1 macrophages were infected with Yersinia pseudotuberculosis strains both able and unable to secrete full-length translocon YopB for 1 hour. Levels of TNF-alpha in media were quantified, with YopB mutants consistently producing twofold more TNF-alpha. Yersinia pseudotuberculosis A0A0N9NJG3 should be the protein ID. This is described as an Uncharacterized protein, I chose this protein designation because there is no YopB for Yersinia pseudotuberculosis. |
complete | ||||
|
involved_in |
GO:0009405 |
pathogenesis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009405 |
pathogenesis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Palmer, LE et al. (1998) YopJ of Yersinia pseudotuberculosis is required for the inhibition of macrophage TNF-alpha production and downregulation of the MAP kinases p38 and JNK. Mol. Microbiol. 27 953-65 PubMed GONUTS page
b