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YEAST:THP2
Contents
| Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
| Gene Name(s) | THP2 | |
| Protein Name(s) | THO complex subunit THP2 | |
| External Links | ||
| UniProt | O13539 | |
| EMBL | U00027 BK006934 | |
| PIR | S52609 | |
| RefSeq | NP_012037.1 | |
| ProteinModelPortal | O13539 | |
| BioGrid | 36601 | |
| DIP | DIP-4246N | |
| IntAct | O13539 | |
| MINT | MINT-473610 | |
| STRING | 4932.YHR167W | |
| TCDB | 3.A.22.1.1 | |
| MaxQB | O13539 | |
| PaxDb | O13539 | |
| PeptideAtlas | O13539 | |
| EnsemblFungi | [example_ID YHR167W] | |
| GeneID | 856572 | |
| KEGG | sce:YHR167W | |
| CYGD | YHR167w | |
| SGD | S000001210 | |
| eggNOG | NOG72311 | |
| HOGENOM | HOG000000890 | |
| InParanoid | O13539 | |
| OMA | WTHIENS | |
| OrthoDB | EOG776T33 | |
| BioCyc | YEAST:G3O-31201-MONOMER | |
| NextBio | 982420 | |
| Proteomes | UP000002311 | |
| Genevestigator | O13539 | |
| GO | GO:0000446 GO:0000445 GO:0003676 GO:0006310 GO:0006406 GO:0006355 GO:0000723 GO:0006368 | |
| InterPro | IPR018557 | |
| Pfam | PF09432 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0034063 |
stress granule assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
happens_during:(GO:0097185) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0000723 |
telomere maintenance |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006406 |
mRNA export from nucleus |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006368 |
transcription elongation from RNA polymerase II promoter |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006310 |
DNA recombination |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003676 |
nucleic acid binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000446 |
nucleoplasmic THO complex |
ECO:0000353 |
physical interaction evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000446 |
nucleoplasmic THO complex |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000445 |
THO complex part of transcription export complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000445 |
THO complex part of transcription export complex |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000446 |
nucleoplasmic THO complex |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006368 |
transcription elongation from RNA polymerase II promoter |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006406 |
mRNA export from nucleus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Eshleman, N et al. (2016) Defects in THO/TREX-2 function cause accumulation of novel cytoplasmic mRNP granules that can be cleared by autophagy. RNA 22 1200-14 PubMed GONUTS page
- ↑ Pfeiffer, V et al. (2013) The THO complex component Thp2 counteracts telomeric R-loops and telomere shortening. EMBO J. 32 2861-71 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Strässer, K et al. (2002) TREX is a conserved complex coupling transcription with messenger RNA export. Nature 417 304-8 PubMed GONUTS page
- ↑ 4.0 4.1 Jimeno, S et al. (2002) The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability. EMBO J. 21 3526-35 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Chávez, S et al. (2000) A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae. EMBO J. 19 5824-34 PubMed GONUTS page
