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YEAST:KICH
Contents
| Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
| Gene Name(s) | CKI1 (synonyms: CKI) | |
| Protein Name(s) | Choline kinase | |
| External Links | ||
| UniProt | P20485 | |
| EMBL | J04454 X91258 Z73305 U53881 AY692779 BK006945 | |
| PIR | A32034 | |
| RefSeq | NP_013234.1 | |
| ProteinModelPortal | P20485 | |
| SMR | P20485 | |
| BioGrid | 31402 | |
| DIP | DIP-2617N | |
| IntAct | P20485 | |
| MINT | MINT-422889 | |
| STRING | 4932.YLR133W | |
| MaxQB | P20485 | |
| PaxDb | P20485 | |
| PeptideAtlas | P20485 | |
| EnsemblFungi | [example_ID YLR133W] | |
| GeneID | 850824 | |
| KEGG | sce:YLR133W | |
| CYGD | YLR133w | |
| SGD | S000004123 | |
| eggNOG | COG0510 | |
| GeneTree | ENSGT00530000062991 | |
| HOGENOM | HOG000246747 | |
| InParanoid | P20485 | |
| KO | K00866 | |
| OMA | KFCHNDT | |
| OrthoDB | EOG7WT48T | |
| BioCyc | MetaCyc:MONOMER-13669 YEAST:YLR133W-MONOMER | |
| Reactome | REACT_188974 REACT_189324 | |
| UniPathway | UPA00753 | |
| NextBio | 967079 | |
| Proteomes | UP000002311 | |
| Genevestigator | P20485 | |
| GO | GO:0005737 GO:0005524 GO:0004103 GO:0004305 GO:0006657 GO:0006656 GO:0006646 | |
| InterPro | IPR026712 IPR007521 IPR011009 | |
| PANTHER | PTHR22603:SF32 | |
| Pfam | PF04428 | |
| SUPFAM | SSF56112 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0004103 |
choline kinase activity |
ECO:0000315 |
F |
Table 4 shows the close relationship between choline kinase activity and ethanolamine kinase activity. The wild type had both choline kinase activity and ethanolamine kinase activity. pCK1D overproduced choline kinase, and it also enhanced the ethanolamine kinase activity of the transformant. pCK1G failed to restore the choline kinase activity or the ethanolamine kinase activity. |
complete | |||||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004103 |
choline kinase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006656 |
phosphatidylcholine biosynthetic process |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
SGD:S000002554 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006656 |
phosphatidylcholine biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006646 |
phosphatidylethanolamine biosynthetic process |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
SGD:S000002554 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006646 |
phosphatidylethanolamine biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004305 |
ethanolamine kinase activity |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
SGD:S000002554 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004305 |
ethanolamine kinase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004103 |
choline kinase activity |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
SGD:S000002554 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004103 |
choline kinase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004103 |
choline kinase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006657 |
CDP-choline pathway |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0004103 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006657 |
CDP-choline pathway |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0004103 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006657 |
CDP-choline pathway |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0004103 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006657 |
CDP-choline pathway |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0004103 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006657 |
CDP-choline pathway |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004103 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016773 |
phosphotransferase activity, alcohol group as acceptor |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004103 |
choline kinase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016301 |
kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016310 |
phosphorylation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008654 |
phospholipid biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006629 |
lipid metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006656 |
phosphatidylcholine biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00753 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Hosaka, K et al. (1989) Cloning and characterization of the yeast CKI gene encoding choline kinase and its expression in Escherichia coli. J. Biol. Chem. 264 2053-9 PubMed GONUTS page
- ↑ Huh, WK et al. (2003) Global analysis of protein localization in budding yeast. Nature 425 686-91 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 Kim, K et al. (1999) Isolation and characterization of the Saccharomyces cerevisiae EKI1 gene encoding ethanolamine kinase. J. Biol. Chem. 274 14857-66 PubMed GONUTS page
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