XENLA:WN11B

Species (Taxon ID)	Xenopus laevis (African clawed frog). (8355)
Gene Name(s)	wnt11b (synonyms: wnt-11, wnt11)
Protein Name(s)	Protein Wnt-11b Protein Wnt-11 XWnt-11
External Links
UniProt	P49893
EMBL	L23542 BC084745
PIR	I51572
RefSeq	NP_001084327.1
UniGene	Xl.24008
ProteinModelPortal	P49893
IntAct	P49893
GeneID	399441
KEGG	xla:399441
CTD	399441
Xenbase	XB-GENE-6079153
HOVERGEN	HBG001595
KO	K01384
GO	GO:0005737 GO:0005576 GO:0005615 GO:0005886 GO:0043234 GO:0005578 GO:0005109 GO:0019838 GO:0042803 GO:0030295 GO:0005099 GO:0044212 GO:0017147 GO:0060070 GO:0042074 GO:0060027 GO:0009950 GO:0006897 GO:0007507 GO:0060914 GO:0043066 GO:0090090 GO:0060548 GO:0030308 GO:0030336 GO:0045892 GO:0001755 GO:0061101 GO:0035567 GO:0060021 GO:0030335 GO:0010628 GO:0046330 GO:0045860 GO:0090037 GO:0032320 GO:0051496 GO:0045893 GO:0048793 GO:0034394 GO:0006468 GO:0016055 GO:0060071
InterPro	IPR005817 IPR018161
PANTHER	PTHR12027
Pfam	PF00110
PRINTS	PR01349
SMART	SM00097
PROSITE	PS00246

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0035567	non-canonical Wnt signaling pathway	PMID:19906850^[1]	ECO:0000303	author statement without traceable support used in manual assertion		P	Seeded From UniProt	complete
colocalizes_with	GO:0005615	extracellular space	PMID:19906850^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0062023	collagen-containing extracellular matrix	PMID:19906850^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0090090	negative regulation of canonical Wnt signaling pathway	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O96014	P	Seeded From UniProt	complete
involved_in	GO:0090037	positive regulation of protein kinase C signaling	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O96014	P	Seeded From UniProt	complete
involved_in	GO:0061101	neuroendocrine cell differentiation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O96014	P	Seeded From UniProt	complete
involved_in	GO:0060914	heart formation	PMID:12167861^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0060548	negative regulation of cell death	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O96014	P	Seeded From UniProt	complete
involved_in	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	PMID:17663724^[3]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:P51142	P	Seeded From UniProt	complete
involved_in	GO:0060070	canonical Wnt signaling pathway	PMID:19747829^[4]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:P31286	P	Seeded From UniProt	complete
involved_in	GO:0060070	canonical Wnt signaling pathway	PMID:18927149^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0060027	convergent extension involved in gastrulation	PMID:10769246^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0062009	secondary palate development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O96014	P	Seeded From UniProt	complete
involved_in	GO:0051496	positive regulation of stress fiber assembly	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O96014	P	Seeded From UniProt	complete
involved_in	GO:0048793	pronephros development	PMID:19582868^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0046330	positive regulation of JNK cascade	PMID:12167861^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O96014	P	Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O96014	P	Seeded From UniProt	complete
enables	GO:0044212	transcription regulatory region DNA binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O96014	F	Seeded From UniProt	complete
part_of	GO:0032991	protein-containing complex	PMID:19747829^[4]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P31286	C	Seeded From UniProt	complete
part_of	GO:0032991	protein-containing complex	PMID:18927149^[5]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P31286	C	Seeded From UniProt	complete
involved_in	GO:0043066	negative regulation of apoptotic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O96014	P	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	PMID:18927149^[5]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0042074	cell migration involved in gastrulation	PMID:10862746^[8]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q9PUK8	P	Seeded From UniProt	complete
involved_in	GO:0042074	cell migration involved in gastrulation	PMID:18809723^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0042074	cell migration involved in gastrulation	PMID:11128985^[10]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0042074	cell migration involved in gastrulation	PMID:7739543^[11]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0042074	cell migration involved in gastrulation	PMID:10751186^[12]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0035567	non-canonical Wnt signaling pathway	PMID:15857909^[13]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:P51142	P	Seeded From UniProt	complete
involved_in	GO:0035567	non-canonical Wnt signaling pathway	PMID:10769246^[6]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:P51142	P	Seeded From UniProt	complete
involved_in	GO:0035567	non-canonical Wnt signaling pathway	PMID:11128985^[10]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:P51142	P	Seeded From UniProt	complete
involved_in	GO:0035567	non-canonical Wnt signaling pathway	PMID:18927149^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0034394	protein localization to cell surface	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O96014	P	Seeded From UniProt	complete
involved_in	GO:0043547	positive regulation of GTPase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O96014	P	Seeded From UniProt	complete
involved_in	GO:0030336	negative regulation of cell migration	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O96014	P	Seeded From UniProt	complete
involved_in	GO:0030335	positive regulation of cell migration	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O96014	P	Seeded From UniProt	complete
involved_in	GO:0030308	negative regulation of cell growth	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O96014	P	Seeded From UniProt	complete
enables	GO:0030295	protein kinase activator activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O96014	F	Seeded From UniProt	complete
enables	GO:0019838	growth factor binding	PMID:15797385^[14]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q91649	F	Seeded From UniProt	complete
enables	GO:0019838	growth factor binding	PMID:15797385^[14]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P51865	F	Seeded From UniProt	complete
enables	GO:0017147	Wnt-protein binding	PMID:19747829^[4]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P31286	F	Seeded From UniProt	complete
enables	GO:0017147	Wnt-protein binding	PMID:18927149^[5]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P31286	F	Seeded From UniProt	complete
involved_in	GO:0016055	Wnt signaling pathway	PMID:17663724^[3]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:Q9PUK8	P	Seeded From UniProt	complete
involved_in	GO:0016055	Wnt signaling pathway	PMID:10751186^[12]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:Q9PUK8	P	Seeded From UniProt	complete
NOT\|involved_in	GO:0014036	neural crest cell fate specification	PMID:15857909^[13]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O96014	P	Seeded From UniProt	complete
involved_in	GO:0009950	dorsal/ventral axis specification	PMID:17202189^[15]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:Q9DFH4	P	Seeded From UniProt	complete
involved_in	GO:0009950	dorsal/ventral axis specification	PMID:10751186^[12]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:Q9PUK8	P	Seeded From UniProt	complete
involved_in	GO:0009950	dorsal/ventral axis specification	PMID:15797385^[14]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:Q9PUK8	P	Seeded From UniProt	complete
involved_in	GO:0009950	dorsal/ventral axis specification	PMID:18927149^[5]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:P31286	P	Seeded From UniProt	complete
involved_in	GO:0009950	dorsal/ventral axis specification	PMID:15797385^[14]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0009950	dorsal/ventral axis specification	PMID:8306880^[16]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0007507	heart development	PMID:18715946^[17]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0006897	endocytosis	PMID:18809723^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0006468	protein phosphorylation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O96014	P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:10862746^[8]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q9PUK8	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O96014	C	Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:19747829^[4]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:18927149^[5]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q670P5	C	Seeded From UniProt	complete
enables	GO:0005109	frizzled binding	PMID:10862746^[8]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q9PUK8	F	Seeded From UniProt	complete
enables	GO:0005109	frizzled binding	PMID:16274967^[18]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q9PUK8	F	Seeded From UniProt	complete
enables	GO:0005096	GTPase activator activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O96014	F	Seeded From UniProt	complete
NOT\|involved_in	GO:0003129	heart induction	PMID:11159911^[19]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0001755	neural crest cell migration	PMID:15857909^[13]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0032147	activation of protein kinase activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0030295	P	Seeded From UniProt	complete
enables	GO:0005102	signaling receptor binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005817	F	Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005817	C	Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005817	P	Seeded From UniProt	complete
involved_in	GO:0016055	Wnt signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005817	P	Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P	Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964	C	Seeded From UniProt	complete
involved_in	GO:0007369	gastrulation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0306	P	Seeded From UniProt	complete
involved_in	GO:0016055	Wnt signaling pathway	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0879	P	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 Mii, Y & Taira, M (2009) Secreted Frizzled-related proteins enhance the diffusion of Wnt ligands and expand their signalling range. Development 136 4083-8 PubMed GONUTS page
↑ ^2.0 ^2.1 Pandur, P et al. (2002) Wnt-11 activation of a non-canonical Wnt signalling pathway is required for cardiogenesis. Nature 418 636-41 PubMed GONUTS page
↑ ^3.0 ^3.1 Yamanaka, H & Nishida, E (2007) Wnt11 stimulation induces polarized accumulation of Dishevelled at apical adherens junctions through Frizzled7. Genes Cells 12 961-7 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 Cha, SW et al. (2009) Wnt11/5a complex formation caused by tyrosine sulfation increases canonical signaling activity. Curr. Biol. 19 1573-80 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 ^5.6 Cha, SW et al. (2008) Wnt5a and Wnt11 interact in a maternal Dkk1-regulated fashion to activate both canonical and non-canonical signaling in Xenopus axis formation. Development 135 3719-29 PubMed GONUTS page
↑ ^6.0 ^6.1 Tada, M & Smith, JC (2000) Xwnt11 is a target of Xenopus Brachyury: regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway. Development 127 2227-38 PubMed GONUTS page
↑ Tételin, S & Jones, EA (2010) Xenopus Wnt11b is identified as a potential pronephric inducer. Dev. Dyn. 239 148-59 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 Djiane, A et al. (2000) Role of frizzled 7 in the regulation of convergent extension movements during gastrulation in Xenopus laevis. Development 127 3091-100 PubMed GONUTS page
↑ ^9.0 ^9.1 Kim, GH et al. (2008) Ryk cooperates with Frizzled 7 to promote Wnt11-mediated endocytosis and is essential for Xenopus laevis convergent extension movements. J. Cell Biol. 182 1073-82 PubMed GONUTS page
↑ ^10.0 ^10.1 Smith, JC et al. (2000) Xwnt11 and the regulation of gastrulation in Xenopus. Philos. Trans. R. Soc. Lond., B, Biol. Sci. 355 923-30 PubMed GONUTS page
↑ Du, SJ et al. (1995) Identification of distinct classes and functional domains of Wnts through expression of wild-type and chimeric proteins in Xenopus embryos. Mol. Cell. Biol. 15 2625-34 PubMed GONUTS page
↑ ^12.0 ^12.1 ^12.2 Sumanas, S et al. (2000) The putative wnt receptor Xenopus frizzled-7 functions upstream of beta-catenin in vertebrate dorsoventral mesoderm patterning. Development 127 1981-90 PubMed GONUTS page
↑ ^13.0 ^13.1 ^13.2 De Calisto, J et al. (2005) Essential role of non-canonical Wnt signalling in neural crest migration. Development 132 2587-97 PubMed GONUTS page
↑ ^14.0 ^14.1 ^14.2 ^14.3 Tao, Q et al. (2005) Maternal wnt11 activates the canonical wnt signaling pathway required for axis formation in Xenopus embryos. Cell 120 857-71 PubMed GONUTS page
↑ Kofron, M et al. (2007) Wnt11/beta-catenin signaling in both oocytes and early embryos acts through LRP6-mediated regulation of axin. Development 134 503-13 PubMed GONUTS page
↑ Ku, M & Melton, DA (1993) Xwnt-11: a maternally expressed Xenopus wnt gene. Development 119 1161-73 PubMed GONUTS page
↑ Afouda, BA et al. (2008) GATA transcription factors integrate Wnt signalling during heart development. Development 135 3185-90 PubMed GONUTS page
↑ Shibata, M et al. (2005) Role of crescent in convergent extension movements by modulating Wnt signaling in early Xenopus embryogenesis. Mech. Dev. 122 1322-39 PubMed GONUTS page
↑ Schneider, VA & Mercola, M (2001) Wnt antagonism initiates cardiogenesis in Xenopus laevis. Genes Dev. 15 304-15 PubMed GONUTS page

[PMID:19906850-1] 1.0 ^1.1 ^1.2 Mii, Y & Taira, M (2009) Secreted Frizzled-related proteins enhance the diffusion of Wnt ligands and expand their signalling range. Development 136 4083-8 PubMed GONUTS page

[PMID:12167861-2] 2.0 ^2.1 Pandur, P et al. (2002) Wnt-11 activation of a non-canonical Wnt signalling pathway is required for cardiogenesis. Nature 418 636-41 PubMed GONUTS page

[PMID:17663724-3] 3.0 ^3.1 Yamanaka, H & Nishida, E (2007) Wnt11 stimulation induces polarized accumulation of Dishevelled at apical adherens junctions through Frizzled7. Genes Cells 12 961-7 PubMed GONUTS page

[PMID:19747829-4] 4.0 ^4.1 ^4.2 ^4.3 Cha, SW et al. (2009) Wnt11/5a complex formation caused by tyrosine sulfation increases canonical signaling activity. Curr. Biol. 19 1573-80 PubMed GONUTS page

[PMID:18927149-5] 5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 ^5.6 Cha, SW et al. (2008) Wnt5a and Wnt11 interact in a maternal Dkk1-regulated fashion to activate both canonical and non-canonical signaling in Xenopus axis formation. Development 135 3719-29 PubMed GONUTS page

[PMID:10769246-6] 6.0 ^6.1 Tada, M & Smith, JC (2000) Xwnt11 is a target of Xenopus Brachyury: regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway. Development 127 2227-38 PubMed GONUTS page

[PMID:19582868-7] Tételin, S & Jones, EA (2010) Xenopus Wnt11b is identified as a potential pronephric inducer. Dev. Dyn. 239 148-59 PubMed GONUTS page

[PMID:10862746-8] 8.0 ^8.1 ^8.2 Djiane, A et al. (2000) Role of frizzled 7 in the regulation of convergent extension movements during gastrulation in Xenopus laevis. Development 127 3091-100 PubMed GONUTS page

[PMID:18809723-9] 9.0 ^9.1 Kim, GH et al. (2008) Ryk cooperates with Frizzled 7 to promote Wnt11-mediated endocytosis and is essential for Xenopus laevis convergent extension movements. J. Cell Biol. 182 1073-82 PubMed GONUTS page

[PMID:11128985-10] 10.0 ^10.1 Smith, JC et al. (2000) Xwnt11 and the regulation of gastrulation in Xenopus. Philos. Trans. R. Soc. Lond., B, Biol. Sci. 355 923-30 PubMed GONUTS page

[PMID:7739543-11] Du, SJ et al. (1995) Identification of distinct classes and functional domains of Wnts through expression of wild-type and chimeric proteins in Xenopus embryos. Mol. Cell. Biol. 15 2625-34 PubMed GONUTS page

[PMID:10751186-12] 12.0 ^12.1 ^12.2 Sumanas, S et al. (2000) The putative wnt receptor Xenopus frizzled-7 functions upstream of beta-catenin in vertebrate dorsoventral mesoderm patterning. Development 127 1981-90 PubMed GONUTS page

[PMID:15857909-13] 13.0 ^13.1 ^13.2 De Calisto, J et al. (2005) Essential role of non-canonical Wnt signalling in neural crest migration. Development 132 2587-97 PubMed GONUTS page

[PMID:15797385-14] 14.0 ^14.1 ^14.2 ^14.3 Tao, Q et al. (2005) Maternal wnt11 activates the canonical wnt signaling pathway required for axis formation in Xenopus embryos. Cell 120 857-71 PubMed GONUTS page

[PMID:17202189-15] Kofron, M et al. (2007) Wnt11/beta-catenin signaling in both oocytes and early embryos acts through LRP6-mediated regulation of axin. Development 134 503-13 PubMed GONUTS page

[PMID:8306880-16] Ku, M & Melton, DA (1993) Xwnt-11: a maternally expressed Xenopus wnt gene. Development 119 1161-73 PubMed GONUTS page

[PMID:18715946-17] Afouda, BA et al. (2008) GATA transcription factors integrate Wnt signalling during heart development. Development 135 3185-90 PubMed GONUTS page

[PMID:16274967-18] Shibata, M et al. (2005) Role of crescent in convergent extension movements by modulating Wnt signaling in early Xenopus embryogenesis. Mech. Dev. 122 1322-39 PubMed GONUTS page

[PMID:11159911-19] Schneider, VA & Mercola, M (2001) Wnt antagonism initiates cardiogenesis in Xenopus laevis. Genes Dev. 15 304-15 PubMed GONUTS page

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XENLA:WN11B

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