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XENLA:Q66IV2

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Species (Taxon ID) Xenopus laevis (African clawed frog). (8355)
Gene Name(s) abi1 (ECO:0000313 with Xenbase:XB-GENE-942157) (synonyms: MGC84356 (ECO:0000313 with EMBL:AAH81178.1))
Protein Name(s) MGC84356 protein (ECO:0000313 with EMBL:AAH81178.1)
External Links
UniProt Q66IV2
EMBL BC081178
RefSeq NP_001087758.1
UniGene Xl.7665
ProteinModelPortal Q66IV2
SMR Q66IV2
GeneID 447582
KEGG xla:447582
CTD 10006
Xenbase XB-GENE-942157
HOVERGEN HBG050446
GO GO:0005737
GO:0030296
InterPro IPR028457
IPR028456
IPR012849
IPR001452
IPR000727
PANTHER PTHR10460
PTHR10460:SF2
Pfam PF07815
PF00018
PRINTS PR00452
SMART SM00326
SUPFAM SSF50044
PROSITE PS50002
PS50192

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0001654

eye development

PMID:23558677[1]

ECO:0000315

P

FIGURE 1a. shows Knockdown of Abi1 in embryos results in defects in eye development.

complete
CACAO 7455

involved_in

GO:0001654

eye development

PMID:23558677[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0061098

positive regulation of protein tyrosine kinase activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0030296

P

Seeded From UniProt

complete

involved_in

GO:0008154

actin polymerization or depolymerization

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR028456

P

Seeded From UniProt

complete

enables

GO:0030296

protein tyrosine kinase activator activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR028456

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Singh, A et al. (2013) Abelson interactor 1 (ABI1) and its interaction with Wiskott-Aldrich syndrome protein (wasp) are critical for proper eye formation in Xenopus embryos. J. Biol. Chem. 288 14135-46 PubMed GONUTS page