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WB:rib-2

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Species (Taxon ID) Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s) rib-2 ( synonyms: K01G5.6 )
Protein Name(s) No Information Provided.
External Links
WB WBGene00004361

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005515

protein binding

WB_REF:WBPaper00004667
PMID:11121397[1]

IPI: Inferred from Physical Interaction

WB:WBGene00004360

F

From WB

GO:0008375

acetylglucosaminyltransferase activity

WB_REF:WBPaper00029050
PMID:17237233[2]

IDA: Inferred from Direct Assay

F

From WB

GO:0015012

heparan sulfate proteoglycan biosynthetic process

WB_REF:WBPaper00004667
PMID:11121397[1]

IDA: Inferred from Direct Assay

P

From WB

GO:0015012

heparan sulfate proteoglycan biosynthetic process

WB_REF:WBPaper00029050
PMID:17237233[2]

IDA: Inferred from Direct Assay

P

From WB

GO:0015012

heparan sulfate proteoglycan biosynthetic process

WB_REF:WBPaper00029050
PMID:17237233[2]

IPI: Inferred from Physical Interaction

WB:WBGene00004360

P

From WB

GO:0016020

membrane

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR004263

C

From WB

GO:0016021

integral to membrane

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

CBS:TMHMM

C

From WB

GO:0016758

transferase activity, transferring hexosyl groups

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR015338

F

From WB

GO:0019899

enzyme binding

WB_REF:WBPaper00029050
PMID:17237233[2]

IPI: Inferred from Physical Interaction

WB:WBGene00004360

F

From WB

GO:0031227

intrinsic to endoplasmic reticulum membrane

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR015338

C

From WB

GO:0042328

heparan sulfate N-acetylglucosaminyltransferase activity

WB_REF:WBPaper00004667
PMID:11121397[1]

IDA: Inferred from Direct Assay

F

From WB

GO:0048598

embryonic morphogenesis

WB_REF:WBPaper00029050
PMID:17237233[2]

IMP: Inferred from Mutant Phenotype

WB:WBVar00249740

P

From WB

GO:0060465

pharynx development

WB_REF:WBPaper00031153
PMID:16828468[5]

IMP: Inferred from Mutant Phenotype

WB:WBVar00241210
WB:WBVar00249740

P

From WB

contributes_to

GO:0015020

glucuronosyltransferase activity

WB_REF:WBPaper00029050
PMID:17237233[2]

IDA: Inferred from Direct Assay

F

From WB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Kitagawa, H et al. (2001) rib-2, a Caenorhabditis elegans homolog of the human tumor suppressor EXT genes encodes a novel alpha1,4-N-acetylglucosaminyltransferase involved in the biosynthetic initiation and elongation of heparan sulfate. J. Biol. Chem. 276 4834-8 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Kitagawa, H et al. (2007) Expression of rib-1, a Caenorhabditis elegans homolog of the human tumor suppressor EXT genes, is indispensable for heparan sulfate synthesis and embryonic morphogenesis. J. Biol. Chem. 282 8533-44 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Mulder, NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res. 31 315-8 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Camon, E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res. 13 662-72 PubMed GONUTS page
  5. Franks, DM et al. (2006) C. elegans pharyngeal morphogenesis requires both de novo synthesis of pyrimidines and synthesis of heparan sulfate proteoglycans. Dev. Biol. 296 409-20 PubMed GONUTS page
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