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WB:ama-1

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Species (Taxon ID) Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s) ama-1 ( synonyms: F36A4.7, rpb-1 )
Protein Name(s) No Information Provided.
External Links
WB WBGene00000123

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000003

reproduction

WB_REF:WBPaper00004651
PMID:11231151[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00002210
WB:WBPhenotype:0000689

P

From WB

GO:0000003

reproduction

WB_REF:WBPaper00036244
PMID:20419786[2]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00083858
WB:WBPhenotype:0000688

P

From WB

GO:0000003

reproduction

WB_REF:WBPaper00036244
PMID:20419786[2]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00083870
WB:WBPhenotype:0000688

P

From WB

GO:0000003

reproduction

WB_REF:WBPaper00036244
PMID:20419786[2]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00083882
WB:WBPhenotype:0000688

P

From WB

GO:0001055

RNA polymerase II activity

WB_REF:WBPaper00000654
PMID:6630208[3]

IMP: Inferred from Mutant Phenotype

WB:WBVar00088580

F

From WB

GO:0001055

RNA polymerase II activity

WB_REF:WBPaper00001354
PMID:2076819[4]

IMP: Inferred from Mutant Phenotype

WB:WBVar00088580
WB:WBVar00088655

F

From WB

GO:0003677

DNA binding

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000684

F

From WB

GO:0003677

DNA binding

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000722

F

From WB

GO:0003677

DNA binding

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR006592

F

From WB

GO:0003677

DNA binding

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR007066

F

From WB

GO:0003677

DNA binding

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR007073

F

From WB

GO:0003677

DNA binding

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR007075

F

From WB

GO:0003677

DNA binding

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR007080

F

From WB

GO:0003677

DNA binding

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR007081

F

From WB

GO:0003677

DNA binding

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR007083

F

From WB

GO:0003899

DNA-directed RNA polymerase activity

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000722

F

From WB

GO:0003899

DNA-directed RNA polymerase activity

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR006592

F

From WB

GO:0003899

DNA-directed RNA polymerase activity

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR007066

F

From WB

GO:0003899

DNA-directed RNA polymerase activity

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR007073

F

From WB

GO:0003899

DNA-directed RNA polymerase activity

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR007075

F

From WB

GO:0003899

DNA-directed RNA polymerase activity

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR007080

F

From WB

GO:0003899

DNA-directed RNA polymerase activity

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR007081

F

From WB

GO:0003899

DNA-directed RNA polymerase activity

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR007083

F

From WB

GO:0003899

DNA-directed RNA polymerase activity

WB_REF:WBPaper00001191
PMID:2586513[7]

ISS: Inferred from Sequence or Structural Similarity

F

From WB

GO:0005634

nucleus

WB_REF:WBPaper00002044
PMID:7607073[8]

IDA: Inferred from Direct Assay

C

From WB

GO:0005634

nucleus

WB_REF:WBPaper00006475
PMID:14726532[9]

IDA: Inferred from Direct Assay

C

From WB

GO:0005665

DNA-directed RNA polymerase II, core complex

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000684

C

From WB

GO:0006351

transcription, DNA-dependent

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000722

P

From WB

GO:0006351

transcription, DNA-dependent

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR006592

P

From WB

GO:0006351

transcription, DNA-dependent

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR007066

P

From WB

GO:0006351

transcription, DNA-dependent

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR007073

P

From WB

GO:0006351

transcription, DNA-dependent

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR007075

P

From WB

GO:0006351

transcription, DNA-dependent

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR007080

P

From WB

GO:0006351

transcription, DNA-dependent

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR007081

P

From WB

GO:0006351

transcription, DNA-dependent

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR007083

P

From WB

GO:0006351

transcription, DNA-dependent

WB_REF:WBPaper00002567
PMID:8812143[10]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0006366

transcription from RNA polymerase II promoter

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000684

P

From WB

GO:0006479

protein methylation

WB_REF:WBPaper00028483
PMID:16968818[11]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00086513
WB:WBPhenotype:0001383

P

From WB

GO:0006479

protein methylation

WB_REF:WBPaper00028483
PMID:16968818[11]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00086514
WB:WBPhenotype:0001383

P

From WB

GO:0007052

mitotic spindle organization

WB_REF:WBPaper00024624
PMID:15572126[12]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00062632
WB:WBPhenotype:0001102

P

From WB

GO:0007369

gastrulation

WB_REF:WBPaper00002567
PMID:8812143[10]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0008356

asymmetric cell division

WB_REF:WBPaper00003382
PMID:9834181[13]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00065358
WB:WBPhenotype:0001585

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00004476
PMID:11091073[14]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00075670
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00004651
PMID:11231151[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00002210
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00005224
PMID:11960010[15]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00024332
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00005654
PMID:12529635[16]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00008752
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00006395
PMID:14551910[17]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00025404
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00006475
PMID:14726532[9]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00025054
PMID:15791247[18]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00046459
WB:WBPhenotype:0000050

P

From WB

GO:0010458

exit from mitosis

WB_REF:WBPaper00003382
PMID:9834181[13]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00065358
WB:WBPhenotype:0000169

P

From WB

GO:0032502

developmental process

WB_REF:WBPaper00036244
PMID:20419786[2]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00083858
WB:WBPhenotype:0000518

P

From WB

GO:0032502

developmental process

WB_REF:WBPaper00036244
PMID:20419786[2]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00083870
WB:WBPhenotype:0000518

P

From WB

GO:0032502

developmental process

WB_REF:WBPaper00036244
PMID:20419786[2]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00083882
WB:WBPhenotype:0000518

P

From WB

GO:0040010

positive regulation of growth rate

WB_REF:WBPaper00005654
PMID:12529635[16]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00008752
WB:WBPhenotype:0000031

P

From WB

GO:0042789

mRNA transcription from RNA polymerase II promoter

WB_REF:WBPaper00000654
PMID:6630208[3]

IMP: Inferred from Mutant Phenotype

WB:WBVar00088580

P

From WB

GO:0042789

mRNA transcription from RNA polymerase II promoter

WB_REF:WBPaper00001354
PMID:2076819[4]

IMP: Inferred from Mutant Phenotype

WB:WBVar00088580
WB:WBVar00088655

P

From WB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Maeda, I et al. (2001) Large-scale analysis of gene function in Caenorhabditis elegans by high-throughput RNAi. Curr. Biol. 11 171-6 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Kerins, JA et al. (2010) PRP-17 and the pre-mRNA splicing pathway are preferentially required for the proliferation versus meiotic development decision and germline sex determination in Caenorhabditis elegans. Dev. Dyn. 239 1555-72 PubMed GONUTS page
  3. 3.0 3.1 Sanford, T et al. (1983) RNA polymerase II from wild type and alpha-amanitin-resistant strains of Caenorhabditis elegans. J. Biol. Chem. 258 12804-9 PubMed GONUTS page
  4. 4.0 4.1 Rogalski, TM et al. (1990) Mutant Caenorhabditis elegans RNA polymerase II with a 20,000-fold reduced sensitivity to alpha-amanitin. Genetics 126 889-98 PubMed GONUTS page
  5. 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 5.11 5.12 5.13 5.14 5.15 5.16 5.17 5.18 5.19 5.20 5.21 5.22 5.23 5.24 5.25 5.26 Mulder, NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res. 31 315-8 PubMed GONUTS page
  6. 6.00 6.01 6.02 6.03 6.04 6.05 6.06 6.07 6.08 6.09 6.10 6.11 6.12 6.13 6.14 6.15 6.16 6.17 6.18 6.19 6.20 6.21 6.22 6.23 6.24 6.25 6.26 Camon, E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res. 13 662-72 PubMed GONUTS page
  7. Bird, DM & Riddle, DL (1989) Molecular cloning and sequencing of ama-1, the gene encoding the largest subunit of Caenorhabditis elegans RNA polymerase II. Mol. Cell. Biol. 9 4119-30 PubMed GONUTS page
  8. Seydoux, G & Fire, A (1994) Soma-germline asymmetry in the distributions of embryonic RNAs in Caenorhabditis elegans. Development 120 2823-34 PubMed GONUTS page
  9. 9.0 9.1 Walker, AK et al. (2004) An extensive requirement for transcription factor IID-specific TAF-1 in Caenorhabditis elegans embryonic transcription. J. Biol. Chem. 279 15339-47 PubMed GONUTS page
  10. 10.0 10.1 Powell-Coffman, JA et al. (1996) Onset of C. elegans gastrulation is blocked by inhibition of embryonic transcription with an RNA polymerase antisense RNA. Dev. Biol. 178 472-83 PubMed GONUTS page
  11. 11.0 11.1 Bender, LB et al. (2006) MES-4: an autosome-associated histone methyltransferase that participates in silencing the X chromosomes in the C. elegans germ line. Development 133 3907-17 PubMed GONUTS page
  12. Walston, T et al. (2004) Multiple Wnt signaling pathways converge to orient the mitotic spindle in early C. elegans embryos. Dev. Cell 7 831-41 PubMed GONUTS page
  13. 13.0 13.1 Tabara, H et al. (1999) pos-1 encodes a cytoplasmic zinc-finger protein essential for germline specification in C. elegans. Development 126 1-11 PubMed GONUTS page
  14. Kuroyanagi, H et al. (2000) SPK-1, a C. elegans SR protein kinase homologue, is essential for embryogenesis and required for germline development. Mech. Dev. 99 51-64 PubMed GONUTS page
  15. Wallenfang, MR & Seydoux, G (2002) cdk-7 Is required for mRNA transcription and cell cycle progression in Caenorhabditis elegans embryos. Proc. Natl. Acad. Sci. U.S.A. 99 5527-32 PubMed GONUTS page
  16. 16.0 16.1 Kamath, RS et al. (2003) Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421 231-7 PubMed GONUTS page
  17. Simmer, F et al. (2003) Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol. 1 E12 PubMed GONUTS page
  18. Sönnichsen, B et al. (2005) Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans. Nature 434 462-9 PubMed GONUTS page
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