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VIBCH:HLYU

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Species (Taxon ID) Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961). (243277)
Gene Name(s) hlyU
Protein Name(s) Transcriptional activator HlyU
External Links
UniProt P52695
EMBL X66866
AJ002395
AE003852
PIR S37313
RefSeq NP_230327.1
WP_001888967.1
PDB 4K2E
PDBsum 4K2E
ProteinModelPortal P52695
STRING 243277.VC0678
DNASU 2615467
EnsemblBacteria AAF93843
GeneID 2615467
KEGG vch:VC0678
PATRIC 20080473
eggNOG COG0640
OMA SHEVREM
OrthoDB EOG6B3684
BioCyc RETL1328306-WGS:GSTH-3947-MONOMER
VCHO:VC0678-MONOMER
Proteomes UP000000584
GO GO:0003677
GO:0003700
GO:0009405
GO:0006355
GO:0006351
Gene3D 1.10.10.10
InterPro IPR001845
IPR011991
Pfam PF01022
PRINTS PR00778
SMART SM00418
PROSITE PS50987

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0045893

positive regulation of transcription, DNA-dependent

PMID:8231807[1]

ECO:0000315

P

Fig 6: hlyU mutant is shown to have decreased haemolytic activity, meaning it is a positive transcriptional regulator of virulence genes.

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

PMID:10952301[2]

ECO:0000250

sequence similarity evidence used in manual assertion

P

Seeded From UniProt

Missing: with/from

enables

GO:0003700

DNA-binding transcription factor activity

PMID:10952301[2]

ECO:0000250

sequence similarity evidence used in manual assertion

F

Seeded From UniProt

Missing: with/from

enables

GO:0044212

transcription regulatory region DNA binding

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002108422
UniProtKB:Q9HW47

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG12235
PANTHER:PTN002108422

P

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001845

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001845

P

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0843

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Williams, SG et al. (1993) The transcriptional activator HlyU of Vibrio cholerae: nucleotide sequence and role in virulence gene expression. Mol. Microbiol. 9 751-60 PubMed GONUTS page
  2. 2.0 2.1 Heidelberg, JF et al. (2000) DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae. Nature 406 477-83 PubMed GONUTS page
  3. 3.0 3.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page