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VIBCH:GSPE

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Species (Taxon ID) Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961). (243277)
Gene Name(s) epsE
Protein Name(s) Type II secretion system protein E

T2SS protein E Cholera toxin secretion protein EpsE General secretion pathway protein E Type II traffic warden ATPase

External Links
UniProt P37093
EMBL M96172
L33796
AE003852
PIR JU0147
RefSeq NP_232359.1
WP_000138174.1
PDB 1P9R
1P9W
2BH1
4KSR
4KSS
PDBsum 1P9R
1P9W
2BH1
4KSR
4KSS
ProteinModelPortal P37093
SMR P37093
STRING 243277.VC2732
DNASU 2614895
EnsemblBacteria AAF95872
GeneID 2614895
KEGG vch:VC2732
PATRIC 20084482
eggNOG COG2804
KO K02454
OMA CGHNGYR
OrthoDB EOG63Z76W
BioCyc VCHO:VC2732-MONOMER
EvolutionaryTrace P37093
Proteomes UP000000584
GO GO:0005737
GO:0015627
GO:0005524
GO:0008565
GO:0015628
Gene3D 3.40.50.300
InterPro IPR003593
IPR027417
IPR013369
IPR001482
Pfam PF00437
SMART SM00382
SUPFAM SSF52540
TIGRFAMs TIGR02533
PROSITE PS00662

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0019534

toxin transporter activity

PMID:7737119[1]

ECO:0000315

F

Table 1: the mutant type secretes less toxin.

complete

GO:0031235

intrinsic to internal side of plasma membrane

PMID:7737119[1]

ECO:0000315

C

Figure 3: You can see that the protein localizes in the plasma membrane.

complete

enables

GO:0019534

toxin transmembrane transporter activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002016240
UniProtKB:P37093

F

Seeded From UniProt

complete

enables

GO:0016887

ATPase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001250205
UniProtKB:P22608

F

Seeded From UniProt

complete

involved_in

GO:0015628

protein secretion by the type II secretion system

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002016240
UniProtKB:Q00512

P

Seeded From UniProt

complete

part_of

GO:0015627

type II protein secretion system complex

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002016240
UniProtKB:Q00512

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11739
PANTHER:PTN001250205

C

Seeded From UniProt

complete

involved_in

GO:1901998

toxin transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0019534

P

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013369

F

Seeded From UniProt

complete

enables

GO:0008565

protein transporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013369

F

Seeded From UniProt

complete

part_of

GO:0015627

type II protein secretion system complex

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013369

C

Seeded From UniProt

complete

involved_in

GO:0015628

protein secretion by the type II secretion system

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013369

P

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

involved_in

GO:0015031

protein transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0653

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Sandkvist, M et al. (1995) Interaction between the autokinase EpsE and EpsL in the cytoplasmic membrane is required for extracellular secretion in Vibrio cholerae. EMBO J. 14 1664-73 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page