GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
|Status||Page||Date/Time||GO Term (Aspect)||Reference||Evidence||Notes||Links|
|PEPDI:Q45SX3||2013-04-09 12:00:22 CDT||GO:0044650 adhesion of symbiont to host cell (P)||PMID:11705981||ECO:0000314 direct assay evidence used in manual assertion|
Figure 1B shows adherence of Vero cells to purified GST protein (negative control), FliC, FliD, and the crude flagella. Significant adherence is seen in the purified FliD; a weaker adherence is seen in the crude flagella (both FliC and FliD). These results indicate that FliD has a role in cell adhesion during C. difficile infection.
|LACLM:CLPP||2013-04-11 21:25:24 CDT||GO:0006515 misfolded or incompletely synthesized protein catabolic process (P)||PMID:9987112||ECO:0000315 mutant phenotype evidence used in manual assertion|
Figure 5 shows that a clpP mutant strain has a reduced ability to degrade puromycyl-containing polypeptides which are comparable to misfolded proteins. This indicates that ClpP degrades misfolded proteins.
|LACRE:Q9FCU5||2013-04-13 16:36:40 CDT||GO:0044650 adhesion of symbiont to host cell (P)||PMID:16861796||ECO:0000314 direct assay evidence used in manual assertion|
|PEPDI:CH60||2013-04-14 14:52:55 CDT||GO:0044650 adhesion of symbiont to host cell (P)||PMID:11160803||ECO:0000314 direct assay evidence used in manual assertion|
Figure 5 shows the adhesion of C. difficile to Vero cells in the absence and presence of anti-GroEL; adhesion decreases when anti-GroEL is present indicating that GroEL is involved in the attachment of C. difficile to cells.
Annotations challenged by Siriasde
|Status||Author,Group||Page||GO Term (Aspect)||Reference||Evidence||Links||Page history|
|STRCO:FTSZ||GO:0000917 - division septum assembly (P)||PMID:22113698||ECO:0000315 mutant phenotype evidence used in manual assertion||challenge||C: 4|
0 annotations fixed by Siriasde