User:MKaufman

CACAO Spring 2017

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
unacceptable	CAUCN:A0A0H3CBW7	2017-04-22 12:05:21 CDT	GO:0019430 removal of superoxide radicals (P)	PMID:27484774	ECO:0000315 mutant phenotype evidence used in manual assertion	Dps plays an important role in oxidative stress response. Figure 4 shows that cells with a deletion of the Dps gene had significantly less growth under 400 uM conditions compared to wild-type.	challenge
unacceptable	CAUCN:ALKB	2017-04-22 13:17:13 CDT	GO:0006307 DNA dealkylation involved in DNA repair (P)	PMID:9150207	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 4 shows that the survival of Caulobacter crescentus with a deletion in the AlkB gene is compensated 100fold under .01% methyl methane sulfonate conditions. This shows that AlkB plays a role in the cells defense against alkylation.	challenge
updatedbyinstructor	HUMAN:SMAL1	2017-04-22 13:36:08 CDT	GO:0006303 double-strand break repair via nonhomologous end joining (P)	PMID:26089390	ECO:0000315 mutant phenotype evidence used in manual assertion	Human cells with a deletion in Smarcal1 have less frequent double stranded break repair events. This is seen in Figure 5B where cells with the Smarcal1 deletion show a 4fold decrease in DSB repair events compared to wild type.	challenge

acceptable:0
unacceptable:2
requires_changes:0
flagged:0

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history

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