User:Cece.Staley

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
requireschanges	OLICO:Q51326	2012-10-19 21:53:52 CDT	GO:0008805 carbon-monoxide oxygenase activity (F)	PMID:23077613	ECO:0000314 direct assay evidence used in manual assertion	Figure 1 shows that 'Panel (A) compares the sequences of CoxD (295 aa) of O. carboxidovorans and BchI (350 aa) of R. capsulatus employing the UVa FASTA Server '	challenge
requireschanges	MOUSE:MBD5	2012-10-19 22:32:36 CDT	GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly (P)	PMID:23077600	ECO:0000314 direct assay evidence used in manual assertion	Figure 2 shows that 'The Mbd5-knockout mice had significantly smaller body size than their littermates, and the reduction in body weight was accompanied by a reduction in body length.'	challenge
requireschanges	HUMAN:VGFR2	2012-11-12 16:24:18 CST	GO:0004716 receptor signaling protein tyrosine kinase activity (F)	PMID:23139789	ECO:0000314 direct assay evidence used in manual assertion	Figure one shows that 'HUVECs were subjected to geldanamycin (17-DMAG) treatment for indicated times, lysed and processed for immunoblotting (IB) to analyze indicated protein levels. Arrowhead indicates mature VEGFR2; TfR, transferrin receptor. (B) Quantification of mature VEGFR2 levels in control and geldanamycin-treated endothelial cells'	challenge
unacceptable	HUMAN:PKD1	2012-11-15 12:02:09 CST	GO:0004672 protein kinase activity (F)	PMID:23028574	ECO:0000314 direct assay evidence used in manual assertion	Figure 2 shows that '% residual PKD1 kinase activity calculated based on the total kinase activity measured in the absence of inhibitors (DMSO).'	challenge
unacceptable	HUMAN:PKD1	2012-11-15 12:06:15 CST	GO:0004672 protein kinase activity (F)	PMID:23028574	ECO:0000314 direct assay evidence used in manual assertion	Table 1 shows 'PKD1 selective inhibitors with little or no inhibitory activity for PKCα, PKCδ or CAMKIIα.'	challenge
requireschanges	MOUSE:PKD2	2012-11-15 12:25:57 CST	GO:0004672 protein kinase activity (F)	PMID:22311617	ECO:0000269 experimental evidence used in manual assertion	Figure 3 shows 'in vitro migration and in vivo trafficking of WT and PKD2-deficient lymphocytes to secondary lymphoid tissues.'	challenge
unacceptable	MOUSE:PKD2	2012-11-15 12:32:00 CST	GO:0004672 protein kinase activity (F)	PMID:22233340	ECO:0000314 direct assay evidence used in manual assertion	Figure 1 shows that 'PKD2 regulates thymic output.'	challenge
unacceptable	MOUSE:PKD2	2012-11-15 12:35:59 CST	GO:0004672 protein kinase activity (F)	PMID:22233340	ECO:0000314 direct assay evidence used in manual assertion	Figure 5 shows the 'role of PKD2 in thymus development of TCR transgenic mice.'	challenge

acceptable:0
unacceptable:4
requires_changes:4
flagged:0

Annotations challenged by Cece.Staley

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history

0 annotations fixed by Cece.Staley