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User:Bbourgoyne

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Bbourgoyne, STOP SPAMMING CHALLENGES!

You're stating annotations should be IDA when there's no figure, the protein annotated isn't in the paper, and there's nothing in the paper to annotate. Please make more thoughtful challenges, or the judges may not give you credit even when you're right.

Thank you!


CACAO Spring 2015

My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
correctedthroughchallengesDROME:Q9VIE82015-02-06 13:27:37 CSTGO:0003994 aconitate hydratase activity (F)PMID:22493725ECO:0000314 direct assay evidence used in manual assertion

Found in fruit flies and pathogenic to plants; floats in the cytosol of bacteria.

challenge
correctedthroughchallengesBRADU:NIFH2015-02-06 13:46:11 CSTGO:0016163 nitrogenase activity (F)PMID:24062462ECO:0000314 direct assay evidence used in manual assertion

Catalysis of the reaction 8 reduced ferredoxin + H+ + nitrogen +16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16

challenge
unacceptableHUMAN:CO2A12015-02-06 13:51:54 CSTGO:0005202 collagen (F)PMID:25653215ECO:0000314 direct assay evidence used in manual assertion

Load bearing replacement that mimics bone

challenge
unacceptableHELPX:I2DFD62015-02-06 15:06:19 CSTGO:0004096 catalase activity (F)PMID:25603016ECO:0000314 direct assay evidence used in manual assertion

Inhibits ionizing radiation induced apoptosis in hematopoetic stem and progenitor cells

challenge
requireschangesRAT:ADHX2015-02-06 15:08:14 CSTGO:0004022 alcohol dehydrogenase (NAD) activity (F)PMID:25641189ECO:0000314 direct assay evidence used in manual assertion

Catalyzes conversion of an alcohol + NAD+ to an aldehyde or ketone + NADH

challenge
correctedthroughchallengesECOLI:DLD2015-02-06 15:12:48 CSTGO:0008720 D-lactate dehydrogenase activity (F)PMID:25650346ECO:0000314 direct assay evidence used in manual assertion

Can produced enhanced PLA synthesis

challenge
unacceptableHUMAN:ODPX2015-02-06 15:15:04 CSTGO:0004738 pyruvate dehydrogenase activity (F)PMID:25563647ECO:0000314 direct assay evidence used in manual assertion

Underactivity known to cause brain damage post-stroke

challenge
correctedthroughchallengesENTAE:AMO2015-02-06 15:16:38 CSTGO:0008131 primary amine oxidase activity (F)PMID:24672387ECO:0000314 direct assay evidence used in manual assertion

Eliminates airborne methylamine

challenge
unacceptablePIG:Q71KK52015-02-06 15:17:55 CSTGO:0004129 cytochrome-c oxidase activity (F)PMID:25646428ECO:0000314 direct assay evidence used in manual assertion

inner membrane of mitochondria, catalyzes oxygen to water and couples the free energy by pumping protons across the membrane which aids in synthesizing ATP

challenge
correctedthroughchallengesHUMAN:PERT2015-02-06 15:20:22 CSTGO:0004447 iodide peroxidase activity (F)PMID:25595679ECO:0000314 direct assay evidence used in manual assertion

aids in formation of thyroid hormones T3 and T4 and also is inhibited by arsenic trioxide and reduced glutathione

challenge
unacceptableMOUSE:CAPON2015-02-06 15:21:40 CSTGO:0004517 nitric-oxide synthase activity (F)PMID:25621792ECO:0000314 direct assay evidence used in manual assertion

Syntesis of nitrous oxide; insufficient amounts lead to inhibition of brain activity as well as increased ADHD

challenge
unacceptableHUMAN:TYRO2015-02-06 15:23:09 CSTGO:0050371 tyrosine phenol-lyase activity (F)PMID:25654191ECO:0000314 direct assay evidence used in manual assertion

Degrades tyrosine and generates free radicals in the process

challenge
unacceptableHUMAN:TGM22015-02-06 15:24:44 CSTGO:0071078 fibronectin-tissue transglutaminase complex (C)PMID:25561282ECO:0000314 direct assay evidence used in manual assertion

Decreases cell apoptotic rate

challenge
unacceptableSERMA:NUCA2015-02-06 15:26:26 CSTGO:0004518 nuclease activity (F)PMID:25405367ECO:0000314 direct assay evidence used in manual assertion

Catalyzes hydrolysis of ester linkage with nucleic acid

challenge
unacceptableHUMAN:FEN12015-02-06 15:28:14 CSTGO:0004519 endonuclease activity (F)PMID:25650046ECO:0000314 direct assay evidence used in manual assertion

Cold adapted enzyme based on salt dependence

challenge

acceptable:0
unacceptable:9
requires_changes:1
flagged:0

Annotations challenged by Bbourgoyne

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
unacceptableSedmondson,
Team Designated Drinkers
HUMAN:MYGGO:0001570 - vasculogenesis (P)PMID:25649247ECO:0000316 genetic interaction evidence used in manual assertionchallengeC: 2
requireschangesSedmondson,
Team Designated Drinkers
SALTY:ACKAGO:0008776 - acetate kinase activity (F)PMID:25642214ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 4
unacceptableSedmondson,
Team Designated Drinkers
RAT:PLS1GO:0005515 - protein binding (F)PMID:23621864ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 3
correctedthroughchallengesSedmondson,
Team Designated Drinkers
RAT:UT2GO:0015840 - urea transport (P)PMID:23552862ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 4

fixed by Bbourgoyne
unacceptableSedmondson,
Team Designated Drinkers
DROME:PEROGO:0055114 - obsolete oxidation-reduction process (P)PMID:24459295ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 2
unacceptableSedmondson,
Team Designated Drinkers
9SPER:G8J6U4GO:0009523 - photosystem II (C)PMID:25615587ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 2
requireschangesSedmondson,
Team Designated Drinkers
YEAST:SEE1GO:0008168 - methyltransferase activity (F)PMID:23671032ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 2
requireschangesKsenagbe,
Team Mic Drop
HUMAN:RANB9GO:0005829 - cytosol (C)PMID:25659156ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 1
requireschangesSedmondson,
Team Designated Drinkers
HUMAN:EZRIGO:0005515 - protein binding (F)PMID:25618778ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 3
requireschangesSedmondson,
Team Designated Drinkers
MYCAR:ARCAGO:0016990 - arginine deiminase activity (F)PMID:25538192ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 2
requireschangesLperilloux,
Team Ubiquitous Mafia
DROME:Q7KTX7GO:0044743 - protein transmembrane import into intracellular organelle (P)PMID:20194754ECO:0000316 genetic interaction evidence used in manual assertionchallengeC: 1
unacceptableLperilloux,
Team Ubiquitous Mafia
DROME:Q7KTX7GO:0090141 - positive regulation of mitochondrial fission (P)PMID:20194754ECO:0000316 genetic interaction evidence used in manual assertionchallengeC: 1
unacceptableLperilloux,
Team Ubiquitous Mafia
DROME:Q7KTX7GO:0010637 - negative regulation of mitochondrial fusion (P)PMID:20194754ECO:0000316 genetic interaction evidence used in manual assertionchallengeC: 1
unacceptableHbate,
Team Dos Juanitas
HUMAN:ERBB2GO:0001934 - positive regulation of protein phosphorylation (P)PMID:25655188ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 1
unacceptableMrogers,
Team Dos Juanitas
HUMAN:CFTRGO:0005254 - chloride channel activity (F)PMID:25654755ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 2
unacceptableMrogers,
Team Dos Juanitas
HUMAN:CFTRGO:0005254 - chloride channel activity (F)PMID:25654755ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 1
unacceptableHbate,
Team Dos Juanitas
HUMAN:NSD3GO:0008168 - methyltransferase activity (F)PMID:25657825ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 1
unacceptableHbate,
Team Dos Juanitas
HUMAN:HEXAGO:0003824 - catalytic activity (F)PMID:3377590ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 3
correctedthroughchallengesAsingh,
Team Designated Drinkers
HUMAN:TNNC1GO:0030172 - troponin C binding (F)PMID:7852318ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 6

fixed by Brcalk
unacceptableBwagner,
Team Plants Just Wanna Have Sun
ECOLI:MUTSGO:0008301 - DNA binding, bending (F)PMID:24101514ECO:0000317 genomic context evidence used in manual assertionchallengeC: 2

1 annotations fixed by Bbourgoyne

What do the icons mean in the status column?

assessment icons.jpg