TOXGO:RHBL4

Species (Taxon ID)	Toxoplasma gondii. (5811)
Gene Name(s)	ROM4
Protein Name(s)	Rhomboid-like protease 4
External Links
UniProt	Q695T8
EMBL	AY596193 AY704175
ProteinModelPortal	Q695T8
MEROPS	S54.022
GO	GO:0016021 GO:0004252
Gene3D	1.20.1540.10
InterPro	IPR017092 IPR002610 IPR022764
PANTHER	PTHR22936
Pfam	PF01694
PIRSF	PIRSF037023

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0030260	entry into host cell	PMID:20421941	ECO:0000315			P		Figure 3A. Suppression of TgROM4 results in impaired invasion of host cells	complete CACAO 5927
	GO:0060352	cell adhesion molecule production	PMID:20421941	ECO:0000315			P		Figure 7B. Shedding of MIC2 into the supernatant is decreased in the TgROM4 conditional knockout.	complete CACAO 5928
involved_in	GO:0060352	cell adhesion molecule production	PMID:20421941	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0030260	entry into host cell	PMID:20421941	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0004252	serine-type endopeptidase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002610 InterPro:IPR017092 InterPro:IPR022764	F		Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002610	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002610 InterPro:IPR017092 InterPro:IPR022764	C		Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0645	P		Seeded From UniProt	complete
enables	GO:0008236	serine-type peptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0720	F		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
enables	GO:0008233	peptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0645	F		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472 UniProtKB-SubCell:SL-0162	C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
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References

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